ReviewBiophysical journal2006
Bio-microrheology: a frontier in microrheology.
Review in Biophysical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed.
- Chemical Modulation of Optical Forces for Dynamic Light-Driven Materials.ACS photonics · 2026Article
- Effects of Intracellular Force Localization on Cancer Cell Invasion: Revealing Mechanical Trade-offs through Experimentally Validated Computational Models.ACS biomaterials science & engineering · 2026Article
- Giant KASH proteins and ribosomes establish distinct cytoplasmic biophysical properties in vivo.Science advances · 2025Article
- Microrheology: From Video Microscopy to Optical Tweezers.Micromachines · 2025Review
- Subcellular Mechanical Imaging of Erythrocytes with Optically Correlated Scanning Ion Conductance Microscopy.ACS measurement science au · 2025Article
- Thermodynamic uncertainty relation for systems with active Ornstein-Uhlenbeck particles.PNAS nexus · 2025Article
- Phage probes couple to DNA relaxation dynamics to reveal universal behavior across scales and regimes.Soft matter · 2025Article
- Anisotropy, topography and non-newtonian properties of cellular interiors probed by helical magnetic nanobots.Journal of micro-bio robotics · 2025Article
- Small molecular weight epigenetic inhibitors modulate the extracellular matrix during pancreatic acinar ductal metaplasia.Biochemical and biophysical research communications · 2024Article
- Mind the gap: Exploring extracellular spaces in the brain with particle tracking and AI.Biophysical journal · 2024Article
- Diffusion Wave Spectroscopy Microrheological Characterization of Gelling Agarose Solutions.Polymers · 2024Article
- How cytoskeletal crosstalk makes cells move: Bridging cell-free and cell studies.Biophysics reviews · 2024Review
- Shining Light in Mechanobiology: Optical Tweezers, Scissors, and Beyond.ACS photonics · 2024Review
- Fully angularly resolved 3D microrheology with optical tweezers.Rheologica acta · 2024Article
- How it feels in a cell.Trends in cell biology · 2023Review
- Actin crosslinking by α-actinin averts viscous dissipation of myosin force transmission in stress fibers.iScience · 2023Article
- Optical-Tweezers-integrating-Differential-Dynamic-Microscopy maps the spatiotemporal propagation of nonlinear strains in polymer blends and composites.Nature communications · 2022Article
- Review
- Investigation of the Associations between a Nanomaterial's Microrheology and Toxicology.ACS omega · 2022Article
- Passive and Active Microrheology for Biomedical Systems.Frontiers in bioengineering and biotechnology · 2022Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Cells continuously adapt to changing conditions through coordinated molecular and mechanical responses. This adaptation requires the transport of molecules and signaling through intracellular regions with differing material properties, such as variations in viscosity or elasticity. To determine the impact of regional variations on cell structure and physiology, an approach, termed bio-microrheology, or the study of deformation and flow of biological materials at small length scales has emerged. By tracking the thermal and driven motion of probe particles, organelles, or molecules, the local physical environment in distinct subcellular regions can be explored. On the surface or inside cells, tracking the motion of particles can reveal the rheological properties that influence cell features, such as shape and metastatic potential. Cellular microrheology promises to improve our concepts of regional and integrated properties, structures, and transport in live cells. Since bio-microrheology is an evolving methodology, many specific details, such as how to interpret complex combinations of thermally mediated and directed probe transport, remain to be fully explained. This work reviews the current state of the field and discusses the utility and challenges of this emerging approach.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.