ArticlePediatric nephrology (Berlin, Germany)2006
Prognosis of acute renal failure in children.
Article in Pediatric nephrology (Berlin, Germany), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 55 citations in OpenAlex.
- Acute Renal Failure in the Neonate.Journal of pediatric intensive care · 2016Review
- Haemodialysis for paediatric acute kidney injury in a low resource setting: experience from a tertiary hospital in South West Nigeria.Clinical kidney journal · 2016Article
- Risk factors and prognostic factors of acute kidney injury in children: A retrospective study between 2003 and 2013.Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban · 2015Article
- Kidney tubular cell protection; recent findings.Iranian journal of pediatrics · 2014Article
- A pilot study of urinary fibroblast growth factor-2 and epithelial growth factor as potential biomarkers of acute kidney injury in critically ill children.Pediatric nephrology (Berlin, Germany) · 2013Article
- Acute kidney injury and its association with in-hospital mortality among children with acute infections.Pediatric nephrology (Berlin, Germany) · 2013Article
- Clinical profile of acute kidney injury in a pediatric intensive care unit from Southern India: A prospective observational study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2013Article
- Community-acquired acute kidney injury in tropical countries.Nature reviews. Nephrology · 2013Review
- Incidence and etiology of acute kidney injury in southern India.Indian journal of pediatrics · 2013Article
- Pediatric Sepsis - Part I: "Children are not small adults!"The open inflammation journal · 2011Article
- Sepsis in the pediatric cardiac intensive care unit.World journal for pediatric & congenital heart surgery · 2011Article
- A neonate with severe oligo-anuric renal failure during multi-organ failure survived with prolonged renal replacement therapy.NDT plus · 2011Article
- Etiology and outcome of acute kidney injury in children.Pediatric nephrology (Berlin, Germany) · 2010Article
- Application of the new classification criteria of the Acute Kidney Injury Network: a pilot study in a pediatric population.Pediatric nephrology (Berlin, Germany) · 2009Article
- Evaluating and managing neonatal acute renal failure in a resource-poor setting.Indian journal of pediatrics · 2009Article
- Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock.Critical care medicine · 2008Article
- Clinical characteristics and mortality risk prediction in children with acute kidney injury.Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledAcute renal failure (ARF) is the acute loss of renal function over a period of hours or days. Given the poor prognosis of ARF among children, there is some urgency to identifying more effective prognostic indicators for detecting disease onset. Such indicators would help provide the means of selecting patients who would benefit the most from early aggressive treatment. In this study we assessed the etiologic and prognostic indicators of ARF, including several risk factors such as sepsis, respiratory distress, age, among others, in 300 children who were admitted to the Ali Asghar Children's Hospital, Tehran, Iran, from 1990 to 2003. Statistical analysis was performed using multiple regression and chi-square methods, and a score to determine the prognosis of ARF in children was developed.
resultBased on the results of this study the three common causes of ARF are acute tubular necrosis (ATN, 38%), acute glumerulonephritis (24%) and hemolytic uremic syndrome (24.1%). The overall mortality rate among our patients was 24.7%, with the highest risk group being those patients suffering from ischemic ATN. In addition, the correlation (p<0.0005) between the etiology and mortality rate was particularly high in patients with ischemic ATN. Mortality was also high (68%) in children younger than 2 years. Multiple regression models revealed that among those factors that significantly differed between the survivors and nonsurvivors, only the necessity of dialysis (p<0.0005), the use of mechanical ventilation (p=0.05) and disseminated intravascular coagulation (p=0.038) can be regarded as independent determinants of ARF prognosis in children.
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