Evidence map›Paper›PMID 16959966›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2006

Genetics of Streptomyces rimosus, the oxytetracycline producer.

Hrvoje Petković, John Cullum, Daslav Hranueli, Iain S Hunter, Natasa Perić-Concha, Jasenka Pigac, Arinthip Thamchaipenet, Dusica Vujaklija, Paul F Long

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 112 citations in OpenAlex.

  1. Article
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  5. International journal of systematic and evolutionary microbiology · 2025
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  20. "Microbial Wars" in a Stirred Tank Bioreactor: Investigating the Co-Cultures ofFrontiers in bioengineering and biotechnology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 5 countries.

Hrvoje PetkovićBiotechnical Faculty, University of Ljubljana, Ljubljana, Slovenia.
John Cullum
Daslav Hranueli
Iain S Hunter
Natasa Perić-Concha
Jasenka Pigac
Arinthip Thamchaipenet
Dusica Vujaklija
Paul F Long
Rudjer Boskovic Institute · HRUniversity of London · GBKasetsart University · THUniversity of Kaiserslautern · DEUniversity of Ljubljana · SIUniversity of Strathclyde · GBUniversity of Zagreb · HR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From a genetic standpoint, Streptomyces rimosus is arguably the best-characterized industrial streptomycete as the producer of oxytetracycline and other tetracycline antibiotics. Although resistance to these antibiotics has reduced their clinical use in recent years, tetracyclines have an increasing role in the treatment of emerging infections and noninfective diseases. Procedures for in vivo and in vitro genetic manipulations in S. rimosus have been developed since the 1950s and applied to study the genetic instability of S. rimosus strains and for the molecular cloning and characterization of genes involved in oxytetracycline biosynthesis. Recent advances in the methodology of genome sequencing bring the realistic prospect of obtaining the genome sequence of S. rimosus in the near term.

Indexed as

Chromosomes, BacterialGene OrderGenes, BacterialMicroscopy, ElectronModels, GeneticMolecular StructureMultigene FamilyMutationOxytetracyclineStreptomycesOxytetracycline

Identifiers

PMID16959966
PMCPMC1594589
OpenAlexW2115268399

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.