Evidence map›Paper›PMID 16957423›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2006

Influence of sympathetic activity on blood pressure and vascular damage evaluated by means of urinary albumin excretion.

Francisco J Mena-Martín, Juan C Martín-Escudero, Fernando Simal-Blanco, José L Carretero-Ares, Delfín Arzúa-Mouronte, Juan J Castrodeza Sanz, Hortega Study Investigators

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

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  11. White-coat and masked hypertension are associated with albuminuria in a general population: the Hisayama Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2017
    Article
  12. Article
  13. The association of a single-nucleotide polymorphism in CUBN and the risk of albuminuria and cardiovascular disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2014
    Article
  14. Article
  15. Article
  16. Effect of high fat loading in Dahl salt-sensitive rats.Clinical and experimental hypertension (New York, N.Y. : 1993) · 2009
    Article
  17. Potential renovascular hypertension, space missions, and the role of magnesium.International journal of nephrology and renovascular disease · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Francisco J Mena-MartínDepartment of Internal Medicine, Rio Hortega University Hospital, Valladolid, Spain. francisco.javier.mena@hotmail.com.
Juan C Martín-Escudero
Fernando Simal-Blanco
José L Carretero-Ares
Delfín Arzúa-Mouronte
Juan J Castrodeza Sanz
Hortega Study Investigators
Universidad de Valladolid · ESHospital Universitario Río Hortega · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To analyze the influence of sympathetic activity on blood pressure (BP) and its effects on urinary albumin excretion (UAE), the authors carried out a cross-sectional study in their local health coverage area. The following variables were monitored in a representative sample of the general population made up of 495 individuals: anthropometric parameters; blood glucose, creatinine, and lipid levels; 24-hour urinary albumin, norepinephrine, and epinephrine excretion; and BP of patients with known hypertension and newly discovered BP > or =140/90 mm Hg, evaluated by ambulatory monitoring. In the multivariate analysis, only gender, systolic BP, and UAE were associated with norepinephrine levels; only gender, systolic BP, and body mass index were associated with epinephrine. After excluding those patients with chronic kidney disease, the multivariate analysis showed a strong association between UAE > or =30 mg/d and elevated norepinephrine and epinephrine levels. The authors concluded that in the subject population there is an association between elevated adrenergic activity and higher UAE, independent of factors such as age and BP.

Indexed as

AdultAgedAged, 80 and overAlbuminuriaBlood PressureCardiovascular SystemCross-Sectional StudiesEpinephrineFemaleHumansHypertensionMaleMiddle AgedNorepinephrineSpainSympathetic Nervous SystemEpinephrineNorepinephrine

Identifiers

PMID16957423
PMCPMC8109635
OpenAlexW2012968926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.