ArticleApplied and environmental microbiology2006
Haloalkane dehalogenase LinB is responsible for beta- and delta-hexachlorocyclohexane transformation in Sphingobium indicum B90A.
Article in Applied and environmental microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Comprehensive review on Haloalkane dehalogenase (LinB): a β-hexachlorocyclohexane (HCH) degrading enzyme.Archives of microbiology · 2024Review
- Assessing HCH isomer uptake in Alnus glutinosa: implications for phytoremediation and microbial response.Scientific reports · 2024Article
- Mycelial nutrient transfer promotes bacterial co-metabolic organochlorine pesticide degradation in nutrient-deprived environments.The ISME journal · 2023Article
- Community-integrated multi-omics facilitates screening and isolation of the organohalide dehalogenation microorganism.Innovation (Cambridge (Mass.)) · 2023Article
- Biodegradation of technical hexachlorocyclohexane by Cupriavidus malaysiensis.World journal of microbiology & biotechnology · 2022Article
- Kinetic and Structural Characterization of the First B3 Metallo-β-Lactamase with an Active-Site Glutamic Acid.Antimicrobial agents and chemotherapy · 2021Article
- Myco-remediation of Chlorinated Pesticides: Insights Into Fungal Metabolic System.Indian journal of microbiology · 2021Review
- Comparative proteomics unravelled the hexachlorocyclohexane (HCH) isomers specific responses in an archetypical HCH degrading bacterium Sphingobium indicum B90A.Environmental science and pollution research international · 2021Article
- Potency of Phlebia species of white rot fungi for the aerobic degradation, transformation and mineralization of lindane.Journal of microbiology (Seoul, Korea) · 2020Article
- Presence, Diversity, and Enrichment of Respiratory Reductive Dehalogenase and Non-respiratory Hydrolytic and Oxidative Dehalogenase Genes in Terrestrial Environments.Frontiers in microbiology · 2019Article
- Genome Organization of Sphingobium indicum B90A: An Archetypal Hexachlorocyclohexane (HCH) Degrading Genotype.Genome biology and evolution · 2017Article
- Metagenomic Analysis of a Complex Community Present in Pond Sediment.Journal of genomics · 2017Article
- Novel LinA type 3 δ-hexachlorocyclohexane dehydrochlorinase.Applied and environmental microbiology · 2015Article
- Pan-genome dynamics of Pseudomonas gene complements enriched across hexachlorocyclohexane dumpsite.BMC genomics · 2015Article
- Draft Genome Sequence of Hexachlorohexane (HCH)-Degrading Sphingobium lucknowense Strain F2T, Isolated from an HCH Dumpsite.Genome announcements · 2014Article
- Reconstructing an ancestral genotype of two hexachlorocyclohexane-degrading Sphingobium species using metagenomic sequence data.The ISME journal · 2014Article
- Stepwise enhancement of catalytic performance of haloalkane dehalogenase LinB towards β-hexachlorocyclohexane.AMB Express · 2014Article
- Crystal structure and site-directed mutagenesis analyses of haloalkane dehalogenase LinB from Sphingobium sp. strain MI1205.Journal of bacteriology · 2013Article
- Genome sequence of Sphingobium indicum B90A, a hexachlorocyclohexane-degrading bacterium.Journal of bacteriology · 2012Article
- Evaluation of hexachlorocyclohexane contamination from the last lindane production plant operating in India.Environmental science and pollution research international · 2011Article
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10 authors.
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Abstract
Incubation of resting cells of Sphingobium indicum B90A, Sphingobium japonicum UT26, and Sphingobium francense Sp+ showed that they were able to transform beta- and delta-hexachlorocyclohexane (beta- and delta-HCH, respectively), the most recalcitrant hexachlorocyclohexane isomers, to pentachlorocyclohexanols, but only resting cells of strain B90A could further transform the pentachlorocyclohexanol intermediates to the corresponding tetrachlorocyclohexanediols. Moreover, experiments with resting cells of Escherichia coli expressing the LinB proteins of strains B90A, UT26, and Sp+ indicated that LinB was responsible for these transformations. Purified LinB proteins from all three strains also effected the formation of the respective pentachlorocyclohexanols. Although the three LinB enzymes differ only marginally with respect to amino acid sequence, they showed interesting differences with respect to substrate specificity. When LinB from strain B90A was incubated with beta- and delta-HCH, the pentachlorocyclohexanol products were further transformed and eventually disappeared from the incubation mixtures. In contrast, the LinB proteins from strains UT26 and Sp+ could not catalyze transformation of the pentachlorocyclohexanols, and these products accumulated in the incubation mixture. A mutant of strain Sp+ lacking linA and linB did not degrade any of the HCH isomers, including beta-HCH, and complementation of this mutant by linB from strain B90A restored the ability to degrade beta- and delta-HCH.
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