ReviewBreast cancer research : BCR2006
Recent translational research: circulating tumor cells in breast cancer patients.
Review in Breast cancer research : BCR, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Relevance of Circulating Tumor Cells as Predictive Markers for Cancer Incidence and Relapse.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Photoacoustic detection of circulating melanoma cells in late stage patients.Journal of innovative optical health sciences · 2020Article
- Approaches to isolation and molecular characterization of disseminated tumor cells.Oncotarget · 2015Review
- A platelet-mimetic paradigm for metastasis-targeted nanomedicine platforms.Biomacromolecules · 2013Article
- Molecular profiling of individual tumor cells by hyperspectral microscopic imaging.Translational research : the journal of laboratory and clinical medicine · 2012Article
- Clinical Relevance of Disseminated Tumor Cells in the Bone Marrow and Circulating Tumor Cells in the Blood of Breast Cancer Patients.Breast care (Basel, Switzerland) · 2009Review
- Clinical relevance associated to the analysis of circulating tumour cells in patients with solid tumours.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2009Review
- Bone marrow microenvironment and tumor progression.Cancer microenvironment : official journal of the International Cancer Microenvironment Society · 2008Article
- Phenotypic and genetic characterization of circulating tumor cells by combining immunomagnetic selection and FICTION techniques.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2008Article
- Bone marrow micrometastasis in breast cancer: review of detection methods, prognostic impact and biological issues.Journal of clinical pathology · 2008Review
- Bone Marrow Micrometastases in Breast Cancer Patients: A Long-Term Follow-up Study.Clinical medicine. Oncology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In breast cancer patients, hematogenous tumor cell dissemination can be detected, even at the single cell level, by applying immunocytochemical and molecular assays. Various methods for the detection of circulating tumor cells in the peripheral blood have been described. Results from recently reported studies suggest that circulating tumor cell levels may serve as a prognostic marker and for the early assessment of therapeutic response in patients with metastatic breast cancer. However, in early-stage breast cancer, the impact of circulating tumor cells is less well established than the presence of disseminated tumor cells in bone marrow; several clinical studies have demonstrated that cells of the latter type are an independent prognostic factor at primary diagnosis. In this article we briefly summarize recent studies examining the presence of circulating tumor cells in the blood and discuss further clinical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.