Evidence map›Paper›PMID 16952966›Full record

ReviewHeart (British Cardiac Society)2007

Prognosis of stable angina pectoris: why we need larger population studies with higher endpoint resolution.

Adam D Timmis, Gene Feder, Harry Hemingway

Abstract readReview
In one paragraph

Review in Heart (British Cardiac Society), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Type D personality and patient-perceived health in nonsignificant coronary artery disease: the TWeesteden mIld STenosis (TWIST) study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013
    Article
  6. Review
  7. Article
  8. Meta-Analysis of Rare Binary Adverse Event Data.Journal of the American Statistical Association · 2012
    Article
  9. Article
  10. Article
  11. Article
  12. Impact of comorbid diabetes on quality of life and perception of angina pain in people with angina registered with general practitioners in the UK.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2008
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam D TimmisCardiac Directorate, Barts and The London NHS Trust, London, UK. adamtimmis@mac.com
Gene Feder
Harry Hemingway

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The prognosis of angina was described as "unhappy" by the Framingham investigators and as little different from that of 1-year survivors of acute myocardial infarction. Yet recent clinical trials now report that angina has a good prognosis with adverse outcomes reduced to "normal levels". These disparate prognostic assessments may not be incompatible, applying as they do to population cohorts (Framingham) and selected participants in clinical trials. Comparisons between studies are further complicated by the absence of agreed case definitions for stable angina (contrast this with acute coronary syndromes). Our recent data show that for patients with recent onset symptoms attending chest pain clinics, angina remains a high-risk diagnosis and although many patients receive symptomatic benefit from revascularisation, prognosis is usually unaffected. This leaves little room for complacency and, with angina the commonest initial manifestation of coronary artery disease, there is the opportunity for early detection, risk stratification and treatment to modify outcomes. Meanwhile, larger population-based studies are needed to define the patient journey from earliest presentation through the various syndrome transitions to coronary or noncardiac death in order to increase understanding of the aetiological and prognostic differences between the different coronary disease phenotypes.

Indexed as

AgedAged, 80 and overAge DistributionAngina PectorisChronic DiseaseClinical Trials as TopicEpidemiologic MethodsFemaleForecastingHumansMaleMiddle AgedPrognosisRegistriesSyndrome

Identifiers

PMID16952966
PMCPMC1994448

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.