Evidence map›Paper›PMID 16952965›Full record

ArticleJournal of bacteriology2006

Transcriptional response of Escherichia coli to TPEN.

Tara K Sigdel, J Allen Easton, Michael W Crowder

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 58 citations in OpenAlex.

  1. Zinc Homeostasis inBiology · 2026
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  2. Deletion ofApplied and environmental microbiology · 2026
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  4. Utilization of amSphere · 2024
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  11. Autogenous regulation in vivo of theRNA (New York, N.Y.) · 2020
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Zinc-Dependent Transcriptional Regulation inFrontiers in microbiology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tara K SigdelDepartment of Chemistry and Biochemistry, 160 Hughes Hall, Miami University, Oxford, OH 45056, USA.
J Allen Easton
Michael W Crowder
Miami University · US

Funding

Zn(II) metallochaperones in E. coliR21GM079411 · NIGMS · MIAMI UNIVERSITY OXFORD · PI CROWDER, MICHAEL W · 2006 to 2007
$380k
NIGMS NIH HHS GM079411NIGMS NIH HHS R21 GM079411
6 · The paper itself

Abstract

DNA microarrays were used to probe the transcriptional response of Escherichia coli to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.

Indexed as

Gene Expression Regulation, BacterialAdaptation, PhysiologicalDown-RegulationEscherichia coliEthylenediaminesGene Expression ProfilingIron Chelating AgentsOligonucleotide Array Sequence AnalysisTranscription, GeneticUp-RegulationEthylenediaminesIron Chelating AgentsN,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine

Identifiers

PMID16952965
PMCPMC1595494
OpenAlexW2134829119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.