ArticleJournal of bacteriology2006
Sequence analysis of the lactococcal plasmid pNP40: a mobile replicon for coping with environmental hazards.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 52 citations in OpenAlex.
- Comparative genomics and methylome profiling ofMicrobial genomics · 2026Article
- Advances in Genetic Transformation of Lactic Acid Bacteria: Overcoming Barriers and Enhancing Plasmid Tools.International journal of molecular sciences · 2025Review
- Effect of TraN key residues involved in DNA binding on pIP501 transfer rates inFrontiers in molecular biosciences · 2024Article
- Analysis of CRISPR-Cas Loci and their Targets in Levilactobacillus brevis.Interdisciplinary sciences, computational life sciences · 2023Article
- Delineation of a lactococcal conjugation system reveals a restriction-modification evasion system.Microbial biotechnology · 2023Article
- Plasmid-Based Gene Expression Systems for Lactic Acid Bacteria: A Review.Microorganisms · 2022Review
- Genetic Dissection of a Prevalent Plasmid-Encoded Conjugation System inFrontiers in microbiology · 2021Article
- TheFrontiers in microbiology · 2019Article
- A Pilin Region Affecting Host Range of theFrontiers in microbiology · 2018Article
- Bacteriocin-Antimicrobial Synergy: A Medical and Food Perspective.Frontiers in microbiology · 2017Review
- Article
- Plasmids from Food Lactic Acid Bacteria: Diversity, Similarity, and New Developments.International journal of molecular sciences · 2015Review
- Isolation of a minireplicon of the plasmid pG6303 of Lactobacillus plantarum G63 and characterization of the plasmid-encoded Rep replication protein.Journal of genetics · 2015Article
- Lantibiotic resistance.Microbiology and molecular biology reviews : MMBR · 2015Review
- Influence of a non-hospital medical care facility on antimicrobial resistance in wastewater.PloS one · 2015Article
- Diversity of integron- and culture-associated antibiotic resistance genes in freshwater floc.Applied and environmental microbiology · 2012Article
- Article
- Article
- Systems solutions by lactic acid bacteria: from paradigms to practice.Microbial cell factories · 2011Review
- Adaptative potential of the Lactococcus lactis IL594 strain encoded in its 7 plasmids.PloS one · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The conjugative lactococcal plasmid pNP40, identified in Lactococcus lactis subsp. diacetylactis DRC3, possesses a potent complement of bacteriophage resistance systems, which has stimulated its application as a fitness-improving, food-grade genetic element for industrial starter cultures. The complete sequence of this plasmid allowed the mapping of previously known functions including replication, conjugation, bacteriocin resistance, heavy metal tolerance, and bacteriophage resistance. In addition, functions for cold shock adaptation and DNA damage repair were identified, further confirming pNP40's contribution to environmental stress protection. A plasmid cointegration event appears to have been part of the evolution of pNP40, resulting in a "stockpiling" of bacteriophage resistance systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.