ArticleRheumatology international2006
The oxidant-antioxidant balance in systemic sclerosis cases with interstitial lung involvement.
Article in Rheumatology international, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 15 citations in OpenAlex.
- Antioxidant status after iloprost treatment in patients with Raynaud's phenomenon secondary to systemic sclerosis.Clinical rheumatology · 2007Trial
- Virus-Induced MicroRNA Modulation and Systemic Sclerosis Disease.Biomedicines · 2024Review
- Malondialdehyde Serum Levels in Patients with Systemic Sclerosis Relate to Dyslipidemia and Low Ventricular Ejection Fraction.Antioxidants (Basel, Switzerland) · 2023Article
- Oxidative Stress and Epigenetics: miRNA Involvement in Rare Autoimmune Diseases.Antioxidants (Basel, Switzerland) · 2023Review
- Oxidative Stress Induced by Reactive Oxygen Species (ROS) and NADPH Oxidase 4 (NOX4) in the Pathogenesis of the Fibrotic Process in Systemic Sclerosis: A Promising Therapeutic Target.Journal of clinical medicine · 2021Review
- Evaluation of oxidant and antioxidant status and relation with prolidase in systemic sclerosis.Wiener klinische Wochenschrift · 2014Article
- Serum antioxidant status in patients with systemic sclerosis.Indian journal of dermatology · 2013Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to assess the plasma oxidant and antioxidant levels in systemic sclerosis (SS) patients with interstitial lung involvement. Twenty-seven female SS patients and 17 healthy female volunteers were included in the study. Plasma levels of oxidants and antioxidants levels were studied of two groups. The median oxidant and antioxidant levels in study and control groups were, MDA 5.2 +/- 0.4/3.7 +/- 0.5 nmol/ml (P < 0.001), NO 45.4 +/- 3.7/34.2 +/- 2.9 nmol/l (P < 0.001), SOD 25.6 +/- 2.3/24.6 +/- 2.0 U/ml (P > 0.05), catalase 99.9 +/- 9.9/140.0 +/- 10.0 U/ml (P < 0.001), vitamin E 20.5 +/- 1.3/22.6 +/- 2.0%mg (P < 0.001), vitamin C 70.6 +/- 8.7/83.5 +/- 7.3 mg/dl (P < 0.001), respectively. There was also no correlation between plasma levels of oxidants-antioxidants levels and disease duration, duration of pulmonary signs, pulmonary function test values, HRCT scores in SS patients (P > 0.05). In our study, the oxidant burden in SS patients with interstitial lung involvement was found to be increased; however no correlation was detected between the severity of lung involvement and oxidant-antioxidant levels.
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