ArticlePediatric nephrology (Berlin, Germany)2006
Idiopathic membranous nephropathy in children.
Article in Pediatric nephrology (Berlin, Germany), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Risk stratification guided treatment and outcomes of pediatric membranous nephropathy.Pediatric nephrology (Berlin, Germany) · 2026Observational
- How to Choose the Right Treatment for Membranous Nephropathy.Medicina (Kaunas, Lithuania) · 2023Review
- Pediatric membranous nephropathy: In the novel antigens era.Frontiers in immunology · 2022Review
- Primary membranous nephropathy in children and adolescents: a single-centre report from South Asia.Pediatric nephrology (Berlin, Germany) · 2021Article
- Treatment Patterns Among Adults and Children With Membranous Nephropathy in the Cure Glomerulonephropathy Network (CureGN).Kidney international reports · 2019Article
- Chapter 7: Idiopathic membranous nephropathy.Kidney international supplements · 2012Article
- Successful treatment and clearing of circulating CD19-positive cells by rituximab in a child with idiopathic membranous nephropathy.Pediatric nephrology (Berlin, Germany) · 2011Article
- Membranous nephropathy in children: clinical presentation and therapeutic approach.Pediatric nephrology (Berlin, Germany) · 2010Review
- Idiopathic membranous nephropathy associated with polycystic kidney disease.Pediatric nephrology (Berlin, Germany) · 2010Article
- An unusual case of loin pain and nephritis.Clinical and experimental nephrology · 2010Article
- Membranous glomerulonephritis: treatment response and outcome in children.Pediatric nephrology (Berlin, Germany) · 2009Article
- Membranous nephritis associated with acquired cytomegalovirus infection in a 19-month-old baby.Pediatric nephrology (Berlin, Germany) · 2009Article
- Evolution of antiglomerular basement membrane glomerulonephritis into membranous glomerulonephritis.Pediatric nephrology (Berlin, Germany) · 2008Review
- Idiopathic membranous nephropathy in pediatric patients: presentation, response to therapy, and long-term outcome.BMC nephrology · 2007Article
- The Clinical Profile and Long-Term Outcome of Children with Membranous Nephropathy, and the Evaluation of Anti-Phospholipase A2 Receptor Antibody Immunohistochemistry in Kidney Biopsy.Indian journal of nephrologyArticle
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Idiopathic membranous nephropathy (MN) is a rare cause of asymptomatic proteinuria (AP) or nephrotic syndrome (NS) in childhood. To improve our understanding of its clinical course, we retrospectively reviewed 19 cases of idiopathic MN seen in our hospital over a period of 28.5 years, i.e., from January 1977 to July 2005. Eight patients (39%) had AP and 11 (61%) presented with NS. All eight AP patients achieved remission, regardless of treatment modality. Oral corticosteroid was given to all 11 NS patients, but only three of them responded to corticosteroid. Of the eight steroid non-responders, three achieved remissions with the addition of cyclosporine, and the five who were not administered additional immunosuppressive drugs had persistent NS. At the latest evaluation, all six NS patients that achieved remission remained free of proteinuria and had a normal renal function. Moreover, two of the 5 steroid non-responders showed persistent nephrotic-range proteinuria but a stable renal function. The remaining three steroid non-responders progressed into chronic renal insufficiency, and this progression was preceded by renal vein thrombosis (RVT) in two of the three patients. Presentation with NS (P=0.045) and the development of RVT (P=0.010) were identified as poor prognostic factors.
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