ArticleEvidence-based complementary and alternative medicine : eCAM2006
Regulatory T cells, a potent immunoregulatory target for CAM researchers: modulating tumor immunity, autoimmunity and alloreactive immunity (III).
Article in Evidence-based complementary and alternative medicine : eCAM, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Unlocking the therapeutic potential of thymus-isolated regulatory T cells.Frontiers in immunology · 2025Review
- Unraveling and Harnessing the Immune Response at the Cell-Biomaterial Interface for Tissue Engineering Purposes.Advanced healthcare materials · 2024Review
- Enhancing Regulatory T Cells to Treat Inflammatory and Autoimmune Diseases.International journal of molecular sciences · 2023Review
- The Role of Exposomes in the Pathophysiology of Autoimmune Diseases I: Toxic Chemicals and Food.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Review
- Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment.European journal of integrative medicine · 2020Review
- Herbal management of hepatocellular carcinoma through cutting the pathways of the common risk factors.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018Review
- Protective function of Bu Shen Huo Xue formula on the immunity of B6AF1 mice with experimental autoimmune premature ovarian failure.Experimental and therapeutic medicine · 2018Article
- Upregulation of cugbp2 increases response of pancreatic cancer cells to chemotherapy.Langenbeck's archives of surgery · 2016Article
- Curcumin a potent cancer preventive agent: Mechanisms of cancer cell killing.Interventional medicine & applied science · 2014Review
- Andrographis paniculata (Burm. f.) Wall. ex Nees: a review of ethnobotany, phytochemistry, and pharmacology.TheScientificWorldJournal · 2014Review
- Article
- Short-term roxithromycin treatment attenuates airway inflammation via MAPK/NF-κB activation in a mouse model of allergic asthma.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2012Article
- Vaccination with photodynamic therapy-treated macrophages induces highly suppressive T-regulatory cells.Photodermatology, photoimmunology & photomedicine · 2011Article
- Cinnamon extract suppresses experimental colitis through modulation of antigen-presenting cells.World journal of gastroenterology · 2011Article
- Review of Pharmacological Effects of Antrodia camphorata and Its Bioactive Compounds.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Immunomodulation of Autoimmune Arthritis by Herbal CAM.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Mesotherapy versus Systemic Therapy in the Treatment of Acute Low Back Pain: A Randomized Trial.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- The Role of Th17 in Neuroimmune Disorders: Target for CAM Therapy. Part I.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- The Traditional Japanese Medicine Rikkunshito Promotes Gastric Emptying via the Antagonistic Action of the 5-HT(3) Receptor Pathway in Rats.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Andrographolide: a new plant-derived antineoplastic entity on horizon.Evidence-based complementary and alternative medicine : eCAM · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Regulatory T (T(reg)) cells are the major arbiter of immune responses, mediating actions through the suppression of inflammatory and destructive immune reactions. Inappropriate T(reg) cell frequency or functionality potentiates the pathogenesis of myriad diseases with ranging magnitudes of severity. Lack of suppressive capability hinders restraint on immune responses involved in autoimmunity and alloreactivity, while excessive suppressive capacity effectively blocks processes necessary for tumor destruction. Although the etiology of dysfunctional T(reg) cell populations is under debate, the ramifications, and their mechanisms, are increasingly brought to light in the medical community. Methods that compensate for aberrant immune regulation may not address the underlying complications; however, they hold promise for the alleviation of debilitating immune system-related disorders. The dominant immunoregulatory nature of T(reg) cells, coupled with recent mechanistic knowledge of natural immunomodulatory compounds, highlights the importance of T(reg) cells to practitioners and researchers of complementary and alternative medicine (CAM).
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.