Evidence map›Paper›PMID 16951057›Full record

ArticleGenetics2006

Testing for effects of recombination rate on nucleotide diversity in natural populations of Arabidopsis lyrata.

Stephen I Wright, John Paul Foxe, Leah DeRose-Wilson, Akira Kawabe, Mark Looseley, Brandon S Gaut, Deborah Charlesworth

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
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  4. Population Genomics of Transitions to Selfing in Brassicaceae Model Systems.Methods in molecular biology (Clifton, N.J.) · 2020
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  17. The impact of linked selection on plant genomic variation.Briefings in functional genomics · 2014
    Article
  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Stephen I WrightDepartment of Biology, York University, Toronto, Ontario, Canada. stephenw@yorku.ca
John Paul Foxe
Leah DeRose-Wilson
Akira Kawabe
Mark Looseley
Brandon S Gaut
Deborah Charlesworth
University of Edinburgh · GBUniversity of California, Irvine · USYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated DNA sequence diversity for loci on chromosomes 1 and 2 in six natural populations of Arabidopsis lyrata and tested for the role of natural selection in structuring genomewide patterns of variability, specifically examining the effects of recombination rate on levels of silent polymorphism. In contrast with theoretical predictions from models of genetic hitchhiking, maximum-likelihood-based analyses of diversity and divergence do not suggest reduction of diversity in the region of suppressed recombination near the centromere of chromosome 1, except in a single population from Russia, in which the pericentromeric region may have undergone a local selective sweep or demographic process that reduced variability. We discuss various possibilities that might explain why nucleotide diversity in most A. lyrata populations is not related to recombination rate, including genic recombination hotspots, and low gene density in the low recombination rate region.

Indexed as

Genetics, PopulationGenetic VariationRecombination, GeneticArabidopsisBase SequenceChromosome MappingChromosomes, PlantLikelihood FunctionsLinkage DisequilibriumPolymorphism, GeneticSelection, Genetic

Identifiers

PMID16951057
PMCPMC1667078
OpenAlexW2165314248

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.