Evidence map›Paper›PMID 16950242›Full record

ArticleDevelopmental biology2006

The echinoderm adhesome.

Charles A Whittaker, Karl-Frederik Bergeron, James Whittle, Bruce P Brandhorst, Robert D Burke, Richard O Hynes

Abstract read
In one paragraph

Article in Developmental biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
19.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 181 citations in OpenAlex.

  1. FASEB bioAdvances · 2026
    Article
  2. Article
  3. Skeletogenic Expression of Integrin Alpha, Talin and Npnt Genes and Npnt Role in Sea Urchin Skeletogenesis.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2026
    Article
  4. Collagen Mechanics.Sub-cellular biochemistry · 2026
    Review
  5. Article
  6. Mechanisms of assembly and remodelling of the extracellular matrix.Nature reviews. Molecular cell biology · 2024
    Review
  7. Article
  8. Review
  9. International journal of molecular sciences · 2024
    Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Structure and evolution of neuronal wiring receptors and ligands.Developmental dynamics : an official publication of the American Association of Anatomists · 2023
    Review
  18. Article
  19. Review
  20. Review

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Charles A WhittakerCenter for Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Karl-Frederik Bergeron
James Whittle
Bruce P Brandhorst
Robert D Burke
Richard O Hynes
Simon Fraser University · CACenter for Cancer Research · USHoward Hughes Medical Institute · USMassachusetts Institute of Technology · USUniversity of Victoria · CA

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Although the development of sea urchin embryos has been studied extensively and clearly involves both cell adhesion and cell migration, rather little is known about the adhesion receptors and extracellular matrix molecules involved. The completion of the genome of Strongylocentrotus purpuratus allows a comprehensive survey of the complement of cell-cell and cell-matrix adhesion molecules in this organism. Furthermore, the phylogenetic position of echinoderms offers the opportunity to compare the complement of adhesion proteins between protostome and deuterostome invertebrates and between invertebrate and vertebrate deuterostomes. Many aspects of development and cell interactions differ among these different taxa and it is likely that analysis of the spectrum of adhesion receptors and extracellular matrix proteins can open up new insights into which molecules have evolved to suit particular developmental processes. In this paper, we report the results of an initial analysis along these lines. The echinoderm adhesome (complement of adhesion-related genes/proteins) is similar overall to that of other invertebrates although there are significant deuterostome-specific innovations and some interesting features previously thought to be chordate or vertebrate specific.

Indexed as

AnimalsCell AdhesionCollagenEchinodermataLamininModels, MolecularPhylogenyPoriferaProtein ConformationProtein SubunitsSea UrchinsCollagenLamininProtein Subunits

Identifiers

PMID16950242
PMCPMC3565218
OpenAlexW2123647329

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.