ReviewThe Journal of physiology2006
Interaction between interstitial cells and smooth muscles in the lower urinary tract and penis.
Review in The Journal of physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed, 63 citations in OpenAlex.
- Insights on Platelet-Derived Growth Factor Receptor α-Positive Interstitial Cells in the Male Reproductive Tract.International journal of molecular sciences · 2024Review
- Propagation of Pacemaker Activity and Peristaltic Contractions in the Mouse Renal Pelvis Rely on CaFunction (Oxford, England) · 2022Article
- β-Adrenoceptor-mediated Relaxation of Urinary Bladder Muscle in β2-Adrenoceptor Knockout Mice.Frontiers in pharmacology · 2016Article
- The characteristics of intrinsic complex micro-contractile activity in isolated strips of the rat bladder.Naunyn-Schmiedeberg's archives of pharmacology · 2015Article
- The actions of prolonged exposure to cholinergic agonists on isolated bladder strips from the rat.Naunyn-Schmiedeberg's archives of pharmacology · 2015Article
- Control of urinary drainage and voiding.Clinical journal of the American Society of Nephrology : CJASN · 2015Review
- Calcium signalling in Cajal-like interstitial cells of the lower urinary tract.Nature reviews. Urology · 2014Review
- Do we understand any more about bladder interstitial cells?-ICI-RS 2013.Neurourology and urodynamics · 2014Review
- Cajal-like interstitial cells as a novel target in detrusor overactivity treatment: true or myth?Central European journal of urology · 2014Review
- Prostaglandin E2 induces spontaneous rhythmic activity in mouse urinary bladder independently of efferent nerves.British journal of pharmacology · 2012Article
- Role of KIT-Positive Interstitial Cells of Cajal in the Urinary Bladder and Possible Therapeutic Target for Overactive Bladder.Advances in urology · 2011Article
- Functions of ICC-like cells in the urinary tract and male genital organs.Journal of cellular and molecular medicine · 2010Review
- Identification of C-kit-positive interstitial cells in the dog lower urinary tract and relationship with smooth muscle and nerves. Hypotheses for a likely pacemaker role.Veterinary medicine international · 2010Article
- Potentiation of carbachol-induced detrusor smooth muscle contractions by beta-adrenoceptor activation.European journal of pharmacology · 2009Article
- A distinct type of cell in myocardium: interstitial Cajal-like cells (ICLCs).Journal of cellular and molecular medicine · 2009Article
- Smooth muscle cell calcium activation mechanisms.The Journal of physiology · 2008Review
- Effects of imatinib mesylate on spontaneous electrical and mechanical activity in smooth muscle of the guinea-pig stomach.British journal of pharmacology · 2008Article
- Evolving mechanisms of action of alverine citrate on phasic smooth muscles.British journal of pharmacology · 2007Article
- Properties of spontaneous Ca2+ transients recorded from interstitial cells of Cajal-like cells of the rabbit urethra in situ.The Journal of physiology · 2007Article
- Involvement of interstitial cells of Cajal in the control of smooth muscle excitability. Proceedings of a symposium. July 22, 2006. Okayama, Japan.The Journal of physiology · 2006Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Smooth muscles in the lower urinary tract and corporal tissue exhibit spontaneous contractile activity which depends on L-type Ca(2+) channels. The mechanism underlying this activity is spontaneous electrical activity which shows varied form and property between these tissues. Recent studies revealed that interstitial cells (ICs) are widely distributed in the genitourinary system, and suggested their involvement in spontaneous muscle activity. ICs in the system are not a simple analogy of interstitial cells of Cajal (ICC) in the gut, which act as electrical pacemaker, but represent variability amongst tissues which may account for individual characteristics of each organ. In the bladder and corporal tissue, where smooth muscle cells are capable of generating spontaneous electrical activity, ICs may modulate smooth muscle activity. ICs in corporal tissue release prostaglandins via cyclooxygenase-2 (COX-2) activity and reinforce not only spontaneous but also nerve-mediated alpha-adrenergic contractions. In the bladder, their fundamental role in the integration of signals between populations of cells has been proposed, and thus changes in ICs may contribute to an overactive bladder, a pathological condition which results from increased excitability in detrusor smooth muscles. In the urethra, ICs may act as electrical pacemakers as do ICC. However, overall contractility of urethral smooth muscles does not necessarily rely on pacemaking of ICs, and thus some population of smooth muscles may also have their own excitability.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.