Evidence map›Paper›PMID 16945743›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2006

Do risk factors influence the diagnostic accuracy of noninvasive coronary angiography with multislice computed tomography?

Joanne D Schuijf, Nico R Mollet, Filippo Cademartiri, J Wouter Jukema, Hildo J Lamb, Albert de Roos, Ernst E van der Wall, Pim J de Feyter, Jeroen J Bax

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Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Anatomy and physiology in coronary artery disease imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  2. Rationale and design of the Measuring Athlete's Risk of Cardiovascular events (MARC) study : The role of coronary CT in the cardiovascular evaluation of middle-aged sportsmen.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2015
    Article
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  9. Negative exercise stress test Does it mean anything?The Libyan journal of medicine · 2007
    Article
  10. CT imaging of the heart.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2006
    Article
  11. Coronary computed tomographic angiography: competitive or complementary?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2006
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Joanne D SchuijfDepartment of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.
Nico R Mollet
Filippo Cademartiri
J Wouter Jukema
Hildo J Lamb
Albert de Roos
Ernst E van der Wall
Pim J de Feyter
Jeroen J Bax

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultislice computed tomography (MSCT) is a relatively new noninvasive imaging modality in the evaluation of patients with suspected coronary artery disease (CAD). Whether diagnostic accuracy is influenced by gender or risk factors for CAD is currently unknown and was evaluated in this study. METHODS AND

resultsIn 197 patients (171 men and 26 women; mean age, 60 +/- 11 years) 16-slice MSCT was performed and compared with invasive coronary angiography at 2 different centers (Leiden and Rotterdam, The Netherlands). Diagnostic accuracy for the detection of 50% luminal narrowing or greater was calculated for all patients combined, as well as for patients with known versus suspected CAD. In addition, diagnostic accuracy was determined in men versus women and in different subsets of patients based on the presence of risk factors for CAD including hypertension, type 2 diabetes mellitus, hypercholesterolemia, and obesity. Only segments with a diameter of 2.0 mm or greater were evaluated, whereas smaller segments and stents were excluded from the analysis. Overall, a sensitivity and specificity of 99% and 86%, respectively, on a patient level were demonstrated, with corresponding positive and negative predictive values of 95% and 96%, respectively. Similar values were observed in the different subsets of patients, with no statistical differences.

conclusionThese findings confirm the high diagnostic accuracy of MSCT, regardless of gender or risk factors.

Indexed as

AgedCoronary AngiographyCoronary Artery DiseaseElectrocardiographyFemaleHumansMaleMiddle AgedPrognosisRadionuclide ImagingRisk FactorsSensitivity and SpecificitySex FactorsTomography, X-Ray Computed

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.