ReviewMycopathologia2006
Biosynthesis of dothistromin.
Review in Mycopathologia, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Density functional theory investigation of adsorption and charge transfer of fungal polyketide mycotoxins on Si, N Co-doped carbon quantum dots.Journal of molecular modeling · 2026Article
- Xanthones and anthraquinones from the soil fungusRSC advances · 2021Article
- Whole Genome Sequence ofFrontiers in microbiology · 2021Article
- The architectures of iterative type I PKS and FAS.Natural product reports · 2018Review
- Condition-dependent co-regulation of genomic clusters of virulence factors in the grapevine trunk pathogen Neofusicoccum parvum.Molecular plant pathology · 2018Article
- Article
- The genome of the emerging barley pathogen Ramularia collo-cygni.BMC genomics · 2016Article
- Role of epoxide hydrolases in lipid metabolism.Biochimie · 2013Review
- Article
- Surveys of non-ribosomal peptide and polyketide assembly lines in fungi and prospects for their analysis in vitro and in vivo.Fungal genetics and biology : FG & B · 2011Review
- Article
- Review
- Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes.BMC evolutionary biology · 2007Article
- Gene duplication, modularity and adaptation in the evolution of the aflatoxin gene cluster.BMC evolutionary biology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dothistromin is a mycotoxin that is remarkably similar in structure to versicolorin B, a precursor of both aflatoxin and sterigmatocystin. Dothistromin-producing fungi also produce related compounds, including some aflatoxin precursors as well as alternative forms of dothistromin. Dothistromin is synthesized by pathogenic species of Dothistroma in the red bands of pine needles associated with needle blight, but is also made in culture where it is strongly secreted into the surrounding medium. Orthologs of aflatoxin and sterigmatocystin biosynthetic genes have been found that are required for the biosynthesis of dothistromin, along with others that are speculated to be involved in the same pathway on the basis of their sequence similarity to aflatoxin genes. An epoxide hydrolase gene that has no homolog in the aflatoxin or sterigmatocystin gene clusters is also clustered with the dothistromin genes, and all these genes appear to be located on a minichromosome in Dothistroma septosporum. The dothistromin genes are expressed at an early stage of growth, suggesting a role in the first stages of plant invasion by the fungus. Future studies are expected to reveal more about the role of dothistromin in needle blight and about the genomic organization and expression of dothistromin genes: these studies will provide for interesting comparisons with these aspects of aflatoxin and sterigmatocystin biosynthesis.
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