ReviewJournal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy2006
Potential benefits and limitations of various strategies to mitigate the impact of an influenza pandemic.
Review in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Allogeneic stem cell transplantation with T cell-depleted grafts for lymphoproliferative malignancies.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2007Trial
- Impact of non-pharmaceutical interventions on URIs and influenza in crowded, urban households.Public health reports (Washington, D.C. : 1974)Trial
- Exercise Participation during the COVID-19 Pandemic: Anxiety, Stress, and Precautionary Behavior.Behavioral sciences (Basel, Switzerland) · 2022Article
- Article
- Strategies for Early Vaccination During Novel Influenza Outbreaks.Scientific reports · 2015Article
- Article
- Communicating risk and promoting disease mitigation measures in epidemics and emerging disease settings.Pathogens and global health · 2014Review
- Prevention of influenza at Hajj: applications for mass gatherings.Journal of the Royal Society of Medicine · 2013Review
- Potential use of school absenteeism record for disease surveillance in developing countries, case study in rural Cambodia.PloS one · 2013Article
- Article
- The impact of non-pharmaceutical interventions for 2009 H1N1 influenza on travel intentions: A model of goal-directed behavior.Tourism management · 2012Article
- Pandemic response lessons from influenza H1N1 2009 in Asia.Respirology (Carlton, Vic.) · 2011Review
- Detection of resistance mutations to antivirals oseltamivir and zanamivir in avian influenza A viruses isolated from wild birds.PloS one · 2011Article
- The open-air treatment of pandemic influenza.American journal of public health · 2009Article
- Major issues and challenges of influenza pandemic preparedness in developing countries.Emerging infectious diseases · 2008Review
- Viral respiratory infections at the Hajj: comparison between UK and Saudi pilgrims.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2008Article
- Virtual epidemic in a virtual city: simulating the spread of influenza in a US metropolitan area.Translational research : the journal of laboratory and clinical medicine · 2008Article
- Transmission of influenza A in human beings.The Lancet. Infectious diseases · 2007Article
- Pandemic influenza planning in nursing homes: are we prepared?Journal of the American Geriatrics Society · 2007Review
- Nonpharmaceutical Interventions for Military Populations During Pandemic Influenza.Turk Silahli Kuvvetleri koruyucu hekimlik bulteni · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent avian influenza outbreaks underscore the importance of improving our preparedness for an impending influenza pandemic. Various strategies, including pharmaceutical interventions (such as vaccines and antivirals) and nonpharmaceutical interventions (such as quarantine, isolation, and social distancing) may be implemented to mitigate the impact of a pandemic. It is necessary to understand the potential benefits and limitations of each strategy to determine the most appropriate strategies to be implemented. In this article, each strategy is reviewed to define its potential benefits and limitations during a pandemic. Vaccines are probably the most effective measure to reduce morbidity and mortality. However, vaccines are not likely to be available at an early stage of a pandemic. The supply of vaccines is most likely to be insufficient due to limited worldwide production capacity. Antivirals, particularly neuraminidase inhibitors, are expected to be effective against a pandemic influenza strain and are the only available pharmaceutical intervention until enough vaccines are produced. Shortage of supply and high cost is still a major limiting factor in amassing large stockpiles of neuraminidase inhibitors. The possible emergence of resistant strains should also be considered. Nonpharmaceutical interventions can be effective in preventing the spread of the virus under certain conditions. The effectiveness of nonpharmaceutical interventions depends on how influenza viruses are transmitted. There are still significant gaps in the scientific evidence of the way in which influenza viruses are transmitted. Further studies should be conducted to define the basic transmission patterns of influenza viruses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.