ReviewPflugers Archiv : European journal of physiology2006
On the activation mechanism of store-operated calcium channels.
Review in Pflugers Archiv : European journal of physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed.
- A supramolecular complex of palmitoylated Orai C-terminal peptide and cyclodextrin targets the plasma membrane to reduce store-operated calcium channel activity.Materials advances · 2026Article
- Computational Model of Complex Calcium Dynamics: Store Operated CaCell biochemistry and biophysics · 2025Article
- Synthetic Biology Meets CaCells · 2024Review
- Vascular mechanotransduction.Physiological reviews · 2023Review
- Differential regulation of CaScience signaling · 2019Article
- BH3 mimetic-elicited CaCell death & disease · 2017Article
- Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium-driven bile uptake.The Journal of physiology · 2016Article
- Hydrogen peroxide activates store-operated Ca(2+) entry in coronary arteries.British journal of pharmacology · 2015Article
- Communication between mast cells and rat submucosal neurons.Pflugers Archiv : European journal of physiology · 2015Article
- Transient receptor potential channels and regulation of lung endothelial permeability.Pulmonary circulation · 2013Review
- STIM1-regulated Ca2+ influx across the apical and the basolateral membrane in colonic epithelium.The Journal of membrane biology · 2013Article
- Orai1-dependent calcium entry promotes skeletal muscle growth and limits fatigue.Nature communications · 2013Article
- Advanced glycation end products acutely impair ca(2+) signaling in bovine aortic endothelial cells.Frontiers in physiology · 2013Article
- Glioblastoma cells express functional cell membrane receptors activated by daily used medical drugs.Journal of cancer research and clinical oncology · 2009Article
- Calcium homeostasis and cone signaling are regulated by interactions between calcium stores and plasma membrane ion channels.PloS one · 2009Article
- The annexins: spatial and temporal coordination of signaling events during cellular stress.Cellular and molecular life sciences : CMLS · 2009Review
- Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton.The Journal of biological chemistry · 2009Article
- TRPing on the lung endothelium: calcium channels that regulate barrier function.Antioxidants & redox signaling · 2009Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of the patch clamp technique has revolutionised our understanding of the life sciences. One area in which it has made an enormous contribution is cellular signalling. In many cell types, calcium influx across the plasma membrane is essential for the regulation of a wide range of critical physiological responses including secretion, gene transcription and cell growth. For many years the calcium influx pathways in non-excitable cells remained unknown, despite their importance in physiological and pathophysiological states. Very careful and insightful work by James Putney led to the formulation of the capacitative calcium entry (store-operated calcium influx) model, in which the process of emptying intracellular calcium stores resulted in the activation of calcium entry channels. Unequivocal evidence for this revolutionary model was provided by patch clamp studies carried out by Markus Hoth and Reinhold Penner, who demonstrated that store depletion activated a novel class of calcium channel called the CRAC channel. This review provides a historical perspective on the development of store-operated calcium influx and how patch clamping resolved a long-standing controversy in cell physiology. The review also discusses current ideas relating to how store emptying opens channels in the plasma membrane.
Indexed as
Identifiers
16944196What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.