SynthesisChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2006
Success and failure of endoscopic third ventriculostomy in young infants: are there different age distributions?
Synthesis in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 90 citations in OpenAlex.
- Surgical management of longstanding overt ventriculomegaly in adults: evaluating the role of endoscopic third ventriculostomy.Langenbeck's archives of surgery · 2025Pooled it
- Endoscopic third ventriculostomy versus shunt for pediatric hydrocephalus: a systematic literature review and meta-analysis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Pooled it
- Ventricular anatomy of hydrocephalus associated with myeloschisis and endoscopic third ventriculostomy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2008Trial
- Experience with surgical evacuation of neonatal brain abscess: A patient series and review of literature.eNeurologicalSci · 2025Article
- Clinical and radiologic criteria to predict endoscopic third ventriculostomy success in non-communicating pediatric hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Current Trends in the Treatment of Pediatric Hydrocephalus: A Narrative Review Centered on the Indications, Safety, Efficacy, and Long-Term Outcomes of Available Treatment Modalities.Children (Basel, Switzerland) · 2024Review
- Article
- Repeat endoscopic third ventriculostomy success rate according to ventriculostoma closure patterns in children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) in non-communicating hydrocephalus (NCH): comparison of outcome profiles in Nigerian children.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Successful endoscopic third ventriculostomy in children depends on age and etiology of hydrocephalus: outcome analysis in 51 pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Article
- Ventricular endoscopy in the pediatric population: review of indications.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Review
- ETV as a last resort.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014Article
- Success rate of endoscopic third ventriculostomy in infants below six months of age with congenital obstructive hydrocephalus (a preliminary study of eight cases).Asian journal of neurosurgery · 2013Article
- Fungal Granuloma following Endoscopic Third Ventriculostomy for Infantile Hydrocephalus.Sultan Qaboos University medical journal · 2013Article
- Pediatric hydrocephalus outcomes: a review.Fluids and barriers of the CNS · 2012Article
- Third ventriculostomy in infants younger than 1 year old.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2012Article
- Endoscopic third ventriculostomy in patients with shunt malfunction.Journal of Korean Neurosurgical Society · 2011Article
- Endoscopic third ventriculostomy for hydrocephalus in children younger than 1 year of age.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2011Article
- Endoscopic third ventriculostomy in previously shunted children: a retrospective study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Article
- Relation between TGF-beta 1 levels in cerebrospinal fluid and ETV outcome in premature newborns with posthemorrhagic hydrocephalus.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePatient's age and etiology of hydrocephalus are the most important factors influencing the success rate of endoscopic third ventriculostomy (ETV). Failure rates are reported to be particularly high in the first year of age. On the basis of our own data and a metaanalysis of the literature, we try to further define the impact of age on ETV success in infants younger than 1 year. MATERIALS AND
methodsOnly patients with a minimum follow-up of 12 months were considered. Between October 1994 and July 2004, 28 patients younger than 1 year underwent ETV in our institution. Age ranged from 8 to 311 days (median 96). The etiology of hydrocephalus was aqueductal stenosis (AS) in all patients (idiopathic in 13, posthemorrhagic in three, postmeningitic in four, and related to CNS or vascular malformation or to tumor in eight). ETV failure was defined as subsequent need for shunt implantation. The metaanalysis of the literature took into account reported series on ETV in infants with detailed data on age and etiology in every single patient.
resultsIn our own patients, ETV was successful in 13 patients and eventually failed in 15. In the ETV success group, the median age was 200 days and the mean age was 176 days (range 13-311 days). In the ETV failure group, the ages were 105 days (median), 117 days (mean), and 8-299 days (range). The differences were not statistically significant. Age distributions in both outcome groups showed a tendency of failures to occur more frequently in the first 2-4 months of life. The separate analysis of patients with idiopathic AS yielded similar figures and distributions. The data from the metaanalysis of the literature corresponded to our own results.
conclusionThere is a clear impact of age on ETV failure rate even when excluding etiological factors. The probability of ETV success gradually increases during the first months of life. The consequence of these findings for decision-making as well as parental counseling is to try to weigh the age of the infant and its estimated impact on ETV success with other factors guiding the decision to perform ETV or shunt in the treatment of obstructive hydrocephalus.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.