ArticleDocumenta ophthalmologica. Advances in ophthalmology2006
The photopic negative response of the flash electroretinogram in retinal vein occlusion.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 56 citations in OpenAlex.
- The oscillatory response of the electroretinogram and neuronal adaptation.Acta ophthalmologica · 2026Review
- The luminance-response function of the photopic negative response (PhNR): analysing different stimulation, recording and measurement approaches.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- Group comparisons of the individual electroretinogram time trajectories for the ascending limb of the b-wave using a raw and registered time series.BMC research notes · 2023Article
- Significant correlations between focal photopic negative response and focal visual sensitivity and ganglion cell complex thickness in glaucomatous eyes.Japanese journal of ophthalmology · 2022Observational
- Clinical electrophysiology of the optic nerve and retinal ganglion cells.Eye (London, England) · 2021Review
- Photopic negative response using a handheld mini-ganzfeld stimulator in healthy adults: normative values, intra- and inter-session variability.Documenta ophthalmologica. Advances in ophthalmology · 2021Article
- Changes of focal macular and full-field electroretinograms after intravitreal aflibercept in patients with central retinal vein occlusion.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- The photopic negative response of the Light-adapted 3.0 ERG in clinical settings.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Comparisons of photopic negative responses elicited by different conditions from glaucomatous eyes.Japanese journal of ophthalmology · 2020Observational
- Impaired Ganglion Cell Function Objectively Assessed by the Photopic Negative Response in Affected and Asymptomatic Members From Brazilian Families With Leber's Hereditary Optic Neuropathy.Frontiers in neurology · 2020Article
- Optimizing a Portable ERG Device for Glaucoma Clinic: The Effect of Interstimulus Frequency on the Photopic Negative Response.Translational vision science & technology · 2018Article
- Intensity response function of the photopic negative response (PhNR): effect of age and test-retest reliability.Documenta ophthalmologica. Advances in ophthalmology · 2017Article
- Test-retest reliability of the multifocal photopic negative response.Documenta ophthalmologica. Advances in ophthalmology · 2017Article
- Relationship between metamorphopsia and foveal microstructure in patients with branch retinal vein occlusion and cystoid macular edema.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2016Article
- Photopic Negative Response Obtained Using a Handheld Electroretinogram Device: Determining the Optimal Measure and Repeatability.Translational vision science & technology · 2016Article
- Photopic negative response in branch retinal vein occlusion with macular edema.International ophthalmology · 2015Article
- The Test-Retest Reliability of the Photopic Negative Response (PhNR).Translational vision science & technology · 2014Article
- Morphological and electrophysiological outcome in prospective intravitreal bevacizumab treatment of macular edema secondary to central retinal vein occlusion.Documenta ophthalmologica. Advances in ophthalmology · 2014Article
- Electroretinographic assessment of retinal function during acute exposure to normobaric hypoxia.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2014Article
- Visual prognostic value of photopic negative response and optical coherence tomography in central retinal vein occlusion after anti-VEGF treatment.Documenta ophthalmologica. Advances in ophthalmology · 2013Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The photopic negative response (PhNR) has recently been shown to be severely affected in central retinal artery occlusion (CRAO), despite relative preservation of the cone b-wave compared to that in the healthy unaffected fellow eye. The aim of this study was to test how the PhNR of the flash electroretinogram (ERG) is affected in human retinal vein occlusion. PhNR was elicited with red stimuli (1 cd s/m2, 5 cd s/m2, and 7 cd s/m2 with 4 ms duration) and blue background (10 cd/m2). Standard Ganzfeld flash ERG was produced according to the ISCEV standard for the clinical electroretinogram (2004). Sixteen patients with central retinal vein occlusion (CRVO), 14 patients with branch retinal vein occlusion (BRVO), and 16 controls were analyzed. The amplitude of the PhNRs was significantly smaller in the CRVO and BRVO eyes than those in the unaffected fellow or control eyes (p = 0.000). There was a significantly greater reduction of PhNR amplitudes than that of other waves including the OPs, rod b-wave, combined a-wave and b-wave, cone a-wave and b-wave, and 30 Hz flicker ERG. Thus, PhNR amplitude in retinal vein occlusion is severely affected. There is a potential role for PhNR in assessing inner retinal damage and evaluating the effect of treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.