Evidence map›Paper›PMID 16943352›Full record

ArticleJournal of clinical microbiology2006

Detection of severe acute respiratory syndrome coronavirus in stool specimens by commercially available real-time reverse transcriptase PCR assays.

L Louie, A E Simor, S Chong, K Luinstra, A Petrich, J Mahony, M Smieja, G Johnson, F Gharabaghi, R Tellier and 8 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 2 countries.

L LouieDepartment of Microbiology, Sunnybrook Health Sciences Centre, B121-2075 Bayview Ave., Toronto, Ontario, Canada M4N 3M5. lisa.louie@sunnybrook.ca
A E Simor
S Chong
K Luinstra
A Petrich
J Mahony
M Smieja
G Johnson
F Gharabaghi
R Tellier
B M Willey
S Poutanen
T Mazzulli
G Broukhanski
F Jamieson
M Louie
S Richardson
Ontario Laboratory Working Group for the Rapid Diagnosis of Emerging Pathogens
St. Joseph’s Healthcare Hamilton · CAMount Sinai Hospital · CAUniversity of Toronto · CAGreat Ormond Street Hospital · GBHealth Sciences Centre · CAHospital for Sick Children · CAProvincial Laboratory of Public Health · CAPublic Health LaboratoryToronto Public Health · CAUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three commercially available real-time reverse transcriptase PCR assays (the Artus RealArt HPA coronavirus LightCycler, the Artus RealArt HPA coronavirus Rotor-Gene, and the EraGen severe acute respiratory syndrome coronavirus POL assay) and three RNA extraction methodologies were evaluated for the detection of severe acute respiratory syndrome coronavirus RNA from 91 stool specimens. The assays' sensitivities were highest (58% to 75%) for specimens obtained 8 to 21 days after symptom onset. The assays were less sensitive when specimens were obtained less than 8 days or more than 21 days after the onset of symptoms. All assays were 100% specific.

Indexed as

FecesHumansReverse Transcriptase Polymerase Chain ReactionRNA, ViralSensitivity and SpecificitySevere acute respiratory syndrome-related coronavirusRNA, Viral

Identifiers

PMID16943352
PMCPMC1698307
OpenAlexW2169863761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.