ArticleProceedings of the National Academy of Sciences of the United States of America2006
Overdominant quantitative trait loci for yield and fitness in tomato.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers.
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111 citing papers in PubMed, 297 citations in OpenAlex.
- Quantitative trait loci associated with improved fruit yield under heat-stress conditions in fresh-market tomato.Frontiers in plant science · 2026Article
- Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice.Plant biotechnology journal · 2025Article
- Quantitative Insights into the Genetic Mechanisms of Crop Heterosis.Advanced genetics (Hoboken, N.J.) · 2025Review
- Phenotypic plasticity of flowering time and plant height related traits in wheat.BMC plant biology · 2025Article
- New QTLs involved in the control of stigma position in tomato.BMC plant biology · 2025Article
- The genetic architecture of gene expression regulation in aFrontiers in plant science · 2025Article
- A novel tomato interspecific (Horticulture research · 2024Article
- Gene expression bias between the subgenomes of allopolyploid hybrids is an emergent property of the kinetics of expression.PLoS computational biology · 2024Article
- Validity of Xiphophorus fish as models for human disease.Disease models & mechanisms · 2024Review
- A systematic dissection in oilseed rape provides insights into the genetic architecture and molecular mechanism of yield heterosis.Plant biotechnology journal · 2023Article
- Introgression of Heterotic Genomic Segments fromPlants (Basel, Switzerland) · 2023Article
- Engineering custom morpho- and chemotypes ofFrontiers in plant science · 2023Review
- Large-scale genomic and transcriptomic profiles of rice hybrids reveal a core mechanism underlying heterosis.Genome biology · 2022Article
- A comparative transcriptomics and eQTL approach identifies SlWD40 as a tomato fruit ripening regulator.Plant physiology · 2022Article
- Inheritance of Secondary Metabolites and Gene Expression Related to Tomato Fruit Quality.International journal of molecular sciences · 2022Article
- Advances in lentil production through heterosis: Evaluating generations and breeding systems.PloS one · 2022Article
- Physico-Chemical, Nutritional, and Sensory Evaluation of Two New Commercial Tomato Hybrids and Their Parental Lines.Plants (Basel, Switzerland) · 2021Article
- Heterosis goes underground.Journal of experimental botany · 2021Article
- Breeding Tomato Hybrids for Flavour: Comparison of GWAS Results Obtained on Lines and F1 Hybrids.Genes · 2021Article
- Molecular basis of heterosis and related breeding strategies reveal its importance in vegetable breeding.Horticulture research · 2021Review
51 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterosis, or hybrid vigor, is a major genetic force that contributes to world food production. The genetic basis of heterosis is not clear, and the importance of loci with overdominant (ODO) effects is debated. One problem has been the use of whole-genome segregating populations, where interactions often mask the effects of individual loci. To assess the contribution of ODO to heterosis in the absence of epistasis, we carried out quantitative genetic and phenotypic analyses on a population of tomato (Solanum lycopersicum) introgression lines (ILs), which carry single marker-defined chromosome segments from the distantly related wild species Solanum pennellii. The ILs revealed 841 quantitative trait loci (QTL) for 35 diverse traits measured in the field on homozygous and heterozygous plants. ILs showing greater reproductive fitness were characterized by the prevalence of ODO QTL, which were virtually absent for the nonreproductive traits. ODO can result from true ODO due to allelic interactions of a single gene or from pseudoODO that involves linked loci with dominant alleles in repulsion. The fact that we detected dominant and recessive QTL for all phenotypic categories but ODO only for the reproductive traits indicates that pseudoODO due to random linkage is unlikely to explain heterosis in the ILs. Thus, we favor the true ODO model involving a single functional Mendelian locus. We propose that the alliance of ODO QTL with higher reproductive fitness was selected for in evolution and was domesticated by man to improve yields of crop plants.
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