ArticleWorld journal of gastroenterology2006
Analysis of differentially expressed proteins in cancerous and normal colonic tissues.
Article in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Hydrophobic protein in colorectal cancer in relation to tumor stages and grades.World journal of gastroenterology · 2010Article
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Authors and funding
5 authors.
Funding
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Abstract
aimTo identify and analyze the differentially expressed proteins in normal and cancerous tissues of four patients suffering from colon cancer.
methodsColon tissues (normal and cancerous) were homogenized and the proteins were extracted using three protein extraction buffers. The extraction buffers were used in an orderly sequence of increasing extraction strength for proteins with hydrophobic properties. The protein extracts were separated using the SDS-PAGE method and the images were captured and analyzed using Quantity One software. The target protein bands were subjected to in-gel digestion with trypsin and finally analyzed using an ESI-ion trap mass spectrometer.
resultsA total of 50 differentially expressed proteins in colonic cancerous and normal tissues were identified.
conclusionMany of the identified proteins have been reported to be involved in the progression of similar or other types of cancers. However, some of the identified proteins have not been reported before. In addition, a number of hypothetical proteins were also identified.
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