Evidence map›Paper›PMID 16937437›Full record

ArticleWorld journal of gastroenterology2006

Mental and physical symptoms associated with lower social support for patients with hepatitis C.

Julie A Blasiole, Laura Shinkunas, Douglas R Labrecque, Robert M Arnold, Susan L Zickmund

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Perceived Stigma in Patients with Autoimmune Hepatitis.Journal of clinical psychology in medical settings · 2024
    Article
  7. Article
  8. Social support and risk of mortality in cirrhosis: A cohort study.JHEP reports : innovation in hepatology · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Evaluation of depression, anxiety and quality of life in hepatitis C patients who treated with direct acting antiviral agents.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2019
    Article
  16. [Incidence of depressive disorders and related independent risk factors in patients with chronic hepatitis C].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
  17. Integrating Care for Patients With Chronic Liver Disease and Mental Health and Substance Use Disorders.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2018
    Article
  18. Quality of Life of Chronic Hepatitis C Patients and Its Associated Factors.Osong public health and research perspectives · 2017
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Julie A BlasioleCenter for Health Equity Research and Promotion, VA Pittsburgh Healthcare System (151C-U) University Drive C, Pittsburgh PA 15240, USA. susan.zickmund@med.va.gov
Laura Shinkunas
Douglas R Labrecque
Robert M Arnold
Susan L Zickmund
VA Pittsburgh Healthcare System · US

Funding

INTERDISCIPLINARY CARDIOVASCULAR RESEARCH FELLOWSHIPT32HL007121 · NHLBI · UNIVERSITY OF IOWA · PI LONDON, BARRY · 1985 to 2020
$15.1M
NHLBI NIH HHS HL07121NHLBI NIH HHS T32 HL007121
6 · The paper itself

Abstract

aimTo systematically examine the impact of the hepatitis C virus (HCV) diagnosis on patients' level of social support in a large-scale study.

methodsPatients evaluated and treated for HCV in a tertiary referral center were enrolled in a cross-sectional study. Demographic data, functional and emotional status as measured by the Hospital Anxiety and Depression Scale (HAD) and the Sickness Impact Profile (SIP), severity of liver disease, mode of acquisition, and physical and psychiatric comorbidities were collected from patients or abstracted from the medical record. All participants completed a semi-structured interview, addressing questions of social support.

resultsA total of 342 patients (mean age 45.2 years; 37% women) were enrolled. Ninety-two (27%) patients described lower levels of support by family and friends. Nearly half of the participants (45%) noted the loss of at least one relationship due to the disease. Fears related to transmitting the disease (25%) were common and often associated with ignorance or even discrimination by others (19%). Nearly one fifth of the patients did not share information about their disease with others to avoid being stigmatized. Lower levels of social support were significantly associated with living alone, being unemployed, being excluded from antiviral therapy, having psychiatric comorbidities, contracting HCV through intravenous drug use, having high levels of anxiety and depression as measured by the HAD and negative mood state as measured by the SIP. Patients reporting lower levels of social support also noted more physical symptoms as measured by the SIP.

conclusionPatients with hepatitis C often face significant social problems, ranging from social isolation to familial stress. The most common concerns reflect a limited insight of patients and their relatives and friends about the disease, the risk factors for its spread, and about potential consequences. Our data suggest that educational interventions targeting support persons and the stressors identified in our findings may lessen or alleviate the social strains patients with hepatitis C experience.

Indexed as

Social IsolationSocial SupportAdultAntiviral AgentsCross-Sectional StudiesData Interpretation, StatisticalFemaleHepatitis CHumansInterpersonal RelationsMaleMiddle AgedPatient ComplianceSeverity of Illness IndexAntiviral Agents

Identifiers

PMID16937437
PMCPMC4087831
OpenAlexW108058495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.