ArticleIndian journal of pediatrics2006
Current status of anti-diarrheal and anti-secretory drugs in the management of acute childhood diarrhea.
Article in Indian journal of pediatrics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 33 citations in OpenAlex.
- Trial
- Antidiarrheal Activity ofBioMed research international · 2022Article
- Evaluation of Antidiarrheal Activity of 80% Methanolic Extract of the Leaves ofEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Evaluation of Various Solvent Extracts ofMolecules (Basel, Switzerland) · 2020Article
- Antidiarrheal Activity of 80% Methanolic Leaf Extract ofEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Witnessing traumatic events and post-traumatic stress disorder: Insights from an animal model.Neuroscience letters · 2015Article
- In vitro antibacterial and time-kill assessment of crude methanolic stem bark extract of Acacia mearnsii de wild against bacteria in shigellosis.Molecules (Basel, Switzerland) · 2012Article
- Pre-hospital management of diarrhoea among caregivers presenting at a tertiary health institution: implications for practice and health education.African health sciences · 2011Article
- Prevalence of cholera in pediatric patients with acute dehydrating diarrhea.Indian journal of pediatrics · 2010Article
- Probiotics in infectious diarrhoea in children: are they indicated?European journal of pediatrics · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Each year 1.8 million children die due to diarrheal diseases. Indiscriminate use of antibiotics has resulted in increasing resistance to commonly used antibiotics. Moreover the recent outbreaks of shigella and cholera have revealed multi-drug resistance strains. There is a need for review of recommended antibiotics for shigellosis. From recent data it emerges that fluoroquinolones should be the first line of therapy and cephalosporins to be used as the second line. Among the anti-cholera antibiotics, tetracyclines which were the drug of choice for adults, has the advantage of high sensitivity and low cost. Single dose doxycycline would have minimal side effects, hence can be the drug of choice even in children. We should not allow the business pressures to force usage of probiotics and racecadotril as their role in the management of acute diarrhea is yet to be established. Nitazoxanide has high efficacy against Cryptosporodial diarrhea only. Strict adherence to the recommendations for the management of acute childhood diarrhea is needed or else we dilute the effect of standard management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.