ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2006
A branched-chain amino acid aminotransferase gene isolated from Hordeum vulgare is differentially regulated by drought stress.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Article
- Cadmium tolerance mediated by GhBCAT12 through branched-chain amino acid degradation via vacuolar sequestration in cotton.Stress biology · 2026Article
- Indole-3-Butyric Acid Enhances Root Formation and Alleviates Low-Temperature Stress in Sugarcane: Molecular Insights and Identification of Candidate Genes.Plants (Basel, Switzerland) · 2025Article
- The branched-chain amino acid-related isoleucic acid: recent research advances.Plant biology (Stuttgart, Germany) · 2025Review
- Physiological, Metabolome and Gene Expression Analyses Reveal the Accumulation and Biosynthesis Pathways of Soluble Sugars and Amino Acids in Sweet Sorghum under Osmotic Stresses.International journal of molecular sciences · 2024Article
- Research progress on branched-chain amino acid aminotransferases.Frontiers in genetics · 2023Review
- The branched-chain amino acid aminotransferase TaBCAT1 modulates amino acid metabolism and positively regulates wheat rust susceptibility.The Plant cell · 2021Article
- Transcriptomic and metabolomic analysis reveals the role of CoA in the salt tolerance of Zygophyllum spp.BMC plant biology · 2020Article
- Shaping Durum Wheat for the Future: Gene Expression Analyses and Metabolites Profiling Support the Contribution of BCAT Genes to Drought Stress Response.Frontiers in plant science · 2020Article
- Comparative Proteomics of Salt-Tolerant and Salt-Sensitive Maize Inbred Lines to Reveal the Molecular Mechanism of Salt Tolerance.International journal of molecular sciences · 2019Article
- Comparative physiological and metabolomics analysis of wheat (Triticum aestivum L.) following post-anthesis heat stress.PloS one · 2018Article
- Comparative metabolite profiling of drought stress in roots and leaves of seven Triticeae species.BMC genomics · 2017Article
- An integrative overview of the molecular and physiological responses of sugarcane under drought conditions.Plant molecular biology · 2017Article
- The fifth leaf and spike organs of barley (Hordeum vulgare L.) display different physiological and metabolic responses to drought stress.BMC plant biology · 2016Article
- Article
- New insights in the sugarcane transcriptome responding to drought stress as revealed by superSAGE.TheScientificWorldJournal · 2012Article
- Functional annotation of the transcriptome of Sorghum bicolor in response to osmotic stress and abscisic acid.BMC genomics · 2011Article
- Branched-chain and aromatic amino acid catabolism into aroma volatiles in Cucumis melo L. fruit.Journal of experimental botany · 2010Article
- Branched-Chain Amino Acid Metabolism in Arabidopsis thaliana.The arabidopsis book · 2010Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Differential display was used to isolate cDNA clones showing differential expression in response to ABA, drought and cold in barley seedling shoots. One drought-regulated cDNA clone (DD12) was further analyzed and found to encode a branched-chain amino acid aminotransferase (HvBCAT-1). A genomic clone was isolated by probing the Morex BAC library with the cDNA clone DD12 and the structure of Hvbcat-1 was elucidated. The coding region is interrupted by six introns and contains a predicted mitochondrial transit peptide. Hvbcat1 was mapped to chromosome 4H. A comparison was made to rice and Arabidopsis genes to identify conserved structural patterns. Complementation of a yeast (Saccharomyces cerevisiae) double knockout strain revealed that HvBCAT-1 can function as the mitochondrial (catabolic) BCATs in vivo. Transcript levels of Hvbcat-1, increased in response to drought stress. As the first enzyme in the branched-chain amino acid (BCAA) catabolic pathway, HvBCAT-1 might have a role in the degradation of BCAA. Degradation of BCAA could serve as a detoxification mechanism that maintains the pool of free branched-chain amino acids at low and non toxic levels, under drought stress conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.