Trial reportAmerican journal of respiratory and critical care medicine2006
A randomized clinical trial of peak flow versus symptom monitoring in older adults with asthma.
Trial report in American journal of respiratory and critical care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.
- Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults.The Cochrane database of systematic reviews · 2013Pooled it
- Between-Visit Asthma Symptom Monitoring With a Scalable Digital Intervention: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Evaluation of a Primary Care-Integrated Mobile Health Intervention to Monitor between-Visit Asthma Symptoms.Applied clinical informatics · 2024Trial
- Impact of pharmacist-led educational interventions on asthma control and adherence: single-blind, randomised clinical trial.International journal of clinical pharmacy · 2021Trial
- Risk factors and clinical outcomes associated with fixed airflow obstruction in older adults with asthma.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2018Trial
- Effects of feedback on the perception of inspiratory resistance in children with persistent asthma: a signal detection approach.Psychosomatic medicine · 2013Trial
- Shared treatment decision making improves adherence and outcomes in poorly controlled asthma.American journal of respiratory and critical care medicine · 2010Trial
- Factors associated with asthma exacerbations during a long-term clinical trial of controller medications in children.The Journal of allergy and clinical immunology · 2008Trial
- Respiratory-Responsive Vocal Biomarker for Asthma Exacerbation Monitoring: Prospective Cohort Study.Journal of medical Internet research · 2025Observational
- Living well with severe asthma.Breathe (Sheffield, England) · 2019Review
- The current state and provisions for elderly patients with asthma.Journal of general and family medicine · 2017Article
- An Official American Thoracic Society Workshop Report: Evaluation and Management of Asthma in the Elderly.Annals of the American Thoracic Society · 2016Article
- Management of asthma in the elderly patient.Clinical interventions in aging · 2013Review
- The Saudi initiative for asthma - 2012 update: Guidelines for the diagnosis and management of asthma in adults and children.Annals of thoracic medicine · 2012Article
- Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop.The Journal of allergy and clinical immunology · 2011Article
- The Saudi Initiative for Asthma.Annals of thoracic medicine · 2009Article
- The Saudi Initiative for Asthma - 2016 update: Guidelines for the diagnosis and management of asthma in adults and children.Annals of thoracic medicineArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine whether peak flow monitoring has value above and beyond symptom monitoring when used as part of an asthma management plan.
methodsFrom a large managed-care organization, 296 adults, aged 50-92 yr, were recruited and randomly assigned in equal numbers to either use of symptoms or peak flow rate (twice daily or "as needed") for asthma monitoring, and monitored every 6 mo for 2 yr. Interventions were delivered in four 90-min small-group classes and included a personalized action plan and coaching in proper use of asthma inhalers.
resultsWe found no significant differences between peak flow rate and symptom monitoring, or between twice-daily and as-needed peak flow monitoring in the primary or secondary study outcomes: health care utilization (acute, nonacute, or total asthma visits), Asthma Quality-of-Life Questionnaire (AQLQ) scores, and lung function. AQLQ scores and prebronchodilator FEV1 increased significantly for both groups between baseline and 6 mo (AQLQ: mean, 0.4 units; 95% confidence interval, 0.3, 0.5; p < 0.0001; FEV1% predicted: mean, 4%). Inhaler technique improved substantially in both groups.
conclusionsPeak flow monitoring has no advantage over symptom monitoring as an asthma management strategy for older adults with moderate-severe asthma when used in a comprehensive asthma management program. Improved outcomes in both groups suggest that understanding proper medication use, regular monitoring of asthma status, and understanding how to respond to changes are of primary importance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.