ArticleInfection and immunity2006
Pulmonary lymphatics are primary sites of Mycobacterium tuberculosis infection in guinea pigs infected by aerosol.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 81 citations in OpenAlex.
- Lung Lymphatics in Edema, Inflammation, and Thrombosis.Arteriosclerosis, thrombosis, and vascular biology · 2025Review
- Tertiary Lymphoid Structures in Tuberculosis: Persistence, Protection, and Pathology.Immunological reviews · 2025Review
- Distinguishing multiple roles of T cell and macrophage involvement in determining lymph node fates during Mycobacterium tuberculosis infection.PLoS computational biology · 2025Article
- Heterogeneity in immune cell composition is associated withFrontiers in immunology · 2024Article
- The lymphatic vasculature in lung function and respiratory disease.Frontiers in medicine · 2023Review
- Imaging peripheral lymphatic dysfunction in chronic conditions.Frontiers in physiology · 2023Review
- Comparative pathology of experimental pulmonary tuberculosis in animal models.Frontiers in veterinary science · 2023Review
- Characterisation and development of histopathological lesions in a guinea pig model ofFrontiers in veterinary science · 2023Article
- Lymphatic Dissemination and Axillary Web Syndrome in Primary Cutaneous Tuberculosis Secondary to Needlestick Injury.Open forum infectious diseases · 2021Article
- Nodular distribution pattern on chest computed tomography (CT) in patients diagnosed with nontuberculous mycobacteria (NTM) infections.Wiener klinische Wochenschrift · 2021Article
- Neutrophils in Tuberculosis: Cell Biology, Cellular Networking and Multitasking in Host Defense.International journal of molecular sciences · 2021Review
- Lymph nodes-The neglected battlefield in tuberculosis.PLoS pathogens · 2020Review
- Humanized Mouse Model Mimicking Pathology of Human Tuberculosis forFrontiers in immunology · 2019Article
- Lymph nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection in macaques.PLoS pathogens · 2018Article
- Endothelial lineage-specific interaction of Mycobacterium tuberculosis with the blood and lymphatic systems.Tuberculosis (Edinburgh, Scotland) · 2018Review
- GI-19007, a Novel Saccharomyces cerevisiae-Based Therapeutic Vaccine against Tuberculosis.Clinical and vaccine immunology : CVI · 2017Article
- Pathology of Tuberculosis: How the Pathology of Human Tuberculosis Informs and Directs Animal Models.Microbiology spectrum · 2017Review
- Whole genome sequencing reveals mycobacterial microevolution among concurrent isolates from sputum and blood in HIV infected TB patients.BMC infectious diseases · 2016Article
- Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis.The Journal of clinical investigation · 2016Article
- The key role of exudative lesions and their encapsulation: lessons learned from the pathology of human pulmonary tuberculosis.Frontiers in microbiology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Mycobacterium tuberculosis causes a lymphatic vasculitis in the lungs of guinea pigs infected by a low-dose aerosol. This observation suggests that in addition to being a direct conduit from the lungs to the regional lymph nodes, pulmonary lymphatics are themselves sites of infection and could be the site of latent infection.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.