ReviewBlood2006
Proteomic approaches to dissect platelet function: Half the story.
Review in Blood, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 67 citations in OpenAlex.
- MicroRNAs as a Potential Quality Measurement Tool of Platelet Concentrate Stored in Blood Banks-A Review.Cells · 2019Review
- Platelet procoagulant phenotype is modulated by a p38-MK2 axis that regulates RTN4/Nogo proximal to the endoplasmic reticulum: utility of pathway analysis.American journal of physiology. Cell physiology · 2018Article
- New frontiers for platelet CD154.Experimental hematology & oncology · 2015Article
- Are Platelets Cells? And if Yes, are They Immune Cells?Frontiers in immunology · 2015Review
- The human platelet: strong transcriptome correlations among individuals associate weakly with the platelet proteome.Biology direct · 2014Article
- Identification of canine platelet proteins separated by differential detergent fractionation for nonelectrophoretic proteomics analyzed by Gene Ontology and pathways analysis.Veterinary medicine (Auckland, N.Z.) · 2014Article
- In vivo evidence for platelet-induced physiological angiogenesis by a COX driven mechanism.PloS one · 2014Article
- The complex transcriptional landscape of the anucleate human platelet.BMC genomics · 2013Article
- Abundance- and Activity-Based Proteomics in Platelet Biology.Current proteomics · 2011Article
- Platelets: versatile modifiers of innate and adaptive immune responses to transplants.Current opinion in organ transplantation · 2011Review
- Genetic regulation of platelet receptor expression and function: application in clinical practice and drug development.Arteriosclerosis, thrombosis, and vascular biology · 2010Review
- Proteome changes in platelets activated by arachidonic acid, collagen, and thrombin.Proteome science · 2010Article
- Significant downregulation of platelet gene expression in metastatic lung cancer.Clinical and translational science · 2010Article
- Article
- Quiescent platelets stimulate angiogenesis and diabetic wound repair.The Journal of surgical research · 2010Article
- Article
- Proteomic and phospho-proteomic profile of human platelets in basal, resting state: insights into integrin signaling.PloS one · 2009Article
- Article
- The platelet proteome.Current opinion in hematology · 2009Review
- Variation in protein levels obtained from human blood cells and biofluids for platelet, peripheral blood mononuclear cell, plasma, urine and saliva proteomics.Genes & nutrition · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Platelets play critical roles in diverse hemostatic and pathologic disorders and are broadly implicated in various biological processes that include inflammation, wound healing, and thrombosis. Recent progress in high-throughput mRNA and protein profiling techniques has advanced our understanding of the biological functions of platelets. Platelet proteomics has been adopted to decode the complex processes that underlie platelet function by identifying novel platelet-expressed proteins, dissecting mechanisms of signal or metabolic pathways, and analyzing functional changes of the platelet proteome in normal and pathologic states. The integration of transcriptomics and proteomics, coupled with progress in bioinformatics, provides novel tools for dissecting platelet biology. In this review, we focus on current advances in platelet proteomic studies, with emphasis on the importance of parallel transcriptomic studies to optimally dissect platelet function. Applications of these global profiling approaches to investigate platelet genetic diseases and platelet-related disorders are also addressed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.