ArticlePediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology2006
Specific fungal exposures, allergic sensitization, and rhinitis in infants.
Article in Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- Risk factors for allergic rhinitis in preschool children: a meta-analysis and systematic review.BMC pediatrics · 2025Pooled it
- Mycobiota composition and changes across pregnancy in patients with gestational diabetes mellitus (GDM).Scientific reports · 2022Article
- Indoor mould exposure, asthma and rhinitis: findings from systematic reviews and recent longitudinal studies.European respiratory review : an official journal of the European Respiratory Society · 2018Review
- Infant fungal communities: current knowledge and research opportunities.BMC medicine · 2017Review
- Fractionation and identification of the allergic proteins inCurrent medical mycology · 2016Article
- Does Specific Fungal Allergen Really Matter?Allergy, asthma & immunology research · 2016Article
- Early-life mold and tree sensitivity is associated with allergic eosinophilic rhinitis at 4 years of age.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2015Article
- Asthma and allergy development: contrasting influences of yeasts and other fungal exposures.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2015Article
- Article
- Visually observed mold and moldy odor versus quantitatively measured microbial exposure in homes.The Science of the total environment · 2010Article
- Exposure matrices of endotoxin, (1→3)-β-d-glucan, fungi, and dust mite allergens in flood-affected homes of New Orleans.The Science of the total environment · 2010Article
- Breast-feeding, aeroallergen sensitization, and environmental exposures during infancy are determinants of childhood allergic rhinitis.The Journal of allergy and clinical immunology · 2010Article
- Fungal Fragments in Moldy Houses: A Field Study in Homes in New Orleans and Southern Ohio.Atmospheric environment (Oxford, England : 1994) · 2007Article
- House dust (1-3)-beta-D-glucan and wheezing in infants.Allergy · 2007Article
- A comparison of proximity and land use regression traffic exposure models and wheezing in infants.Environmental health perspectives · 2007Article
- Relative moldiness index as predictor of childhood respiratory illness.Journal of exposure science & environmental epidemiology · 2007Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
Indoor air quality has become increasingly important as we live in a society where the majority of our time is spent indoors. Specific attention has been drawn to airborne fungal spores as a factor affecting indoor air quality. This study targeted shortcomings of other studies by utilizing long-term air sampling and total fungal spore enumeration to determine associations between health outcomes and fungal spore concentrations. Infants (n = 144) were clinically evaluated and had skin prick tests (SPT) for 17 allergens. Airborne fungal spores were collected using a Button Personal Inhalable Sampler (SKC Inc.) for 48 h at a flow rate of 4 l/min. Sampling was conducted in the spring (March-May) or fall (August-October) in 2003-2004. Fungal spores were analyzed using microscopy-based total counting and identified to the genus/group level. Total spore and individual genus concentrations were analyzed for associations with rhinitis and positive SPT results. Overall, concentrations varied widely, between <2 and 2294 spores/m(3). While no relationship was observed between SPT(+) and total fungal counts, several significant associations were found when analysis was conducted on the various fungal genera and health outcomes. Positive associations were obtained between: Basidiospores and rhinitis (p < 0.01), Penicillium/Aspergillus and SPT(+) to any allergen (p < 0.01), and Alternaria and SPT(+) to any allergen (p < 0.01). Inverse associations were found between: Cladosporium and SPT(+) to any allergen (p < 0.05), and Cladosporium and SPT(+) to aeroallergens (p < 0.05). This study indicates that health outcome may vary by fungal genera; some fungal types may have sensitizing effects while others may have a beneficial role.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.