ArticleCell2006
A transcriptional logic for nuclear reprogramming.
Article in Cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Construction and Influence of Induced Pluripotent Stem Cells on Early Embryo Development in Black Bone Sheep.Biology · 2025Article
- STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury.Nature cell biology · 2020Article
- Cellular Based Strategies for Microvascular Engineering.Stem cell reviews and reports · 2019Review
- A Compendium of Preparation and Application of Stem Cells in Parkinson's Disease: Current Status and Future Prospects.Frontiers in aging neuroscience · 2016Review
- ERK1 and ERK2 regulate embryonic stem cell self-renewal through phosphorylation of Klf4.Nature structural & molecular biology · 2012Article
- Stem cell challenges in the treatment of neurodegenerative disease.CNS neuroscience & therapeutics · 2012Review
- A synthetic small molecule for rapid induction of multiple pluripotency genes in mouse embryonic fibroblasts.Scientific reports · 2012Article
- Rescue of developmental defects by blastocyst stem cell injection: towards elucidation of neomorphic corrective pathways.Journal of cardiovascular translational research · 2010Article
- Blastocyst injection of embryonic stem cells: a simple approach to unveil mechanisms of corrections in mouse models of human disease.Stem cell reviews and reports · 2009Review
- Induced pluripotent stem (iPS) cells: an up-to-the-minute review.F1000 biology reports · 2009Article
Corrections and comments
- Comment on
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Limitations on a differentiated cell's pluripotency can be erased by nuclear transfer or by fusion with embryonic stem cells, but attempts to recapitulate this process of nuclear reprogramming by molecular means have failed. In this issue of Cell, Takahashi and Yamanaka (2006) take a rational approach to identifying a suite of embryonic transcription factors whose overexpression restores pluripotency to adult somatic cells.
Indexed as
Identifiers
16923385What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.