ArticleJournal of clinical pathology1990
Ber-EP4: new monoclonal antibody which distinguishes epithelia from mesothelial.
Article in Journal of clinical pathology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
68 citing papers in PubMed, 386 citations in OpenAlex.
- Detection of HER-2/neu-positive circulating epithelial cells in prostate cancer patients.British journal of cancer · 2004Trial
- Carcinocythemia detection in peripheral blood smears: a literature review.Advances in laboratory medicine · 2026Review
- Cutaneous basaloid squamous cell carcinoma in a captive blue-fronted amazon (Brazilian journal of veterinary medicine · 2025Article
- Epithelial Cell Adhesion Molecule (EpCAM) Expression in Human Tumors: A Comparison with Pan-Cytokeratin and TROP2 in 14,832 Tumors.Diagnostics (Basel, Switzerland) · 2024Article
- Intraoral Basal Cell Carcinoma of Soft Palate: A Diagnostic Dilemma and Review of Literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Metastatic papillary thyroid carcinoma in pleural effusion: a case report and review of the literature.Journal of medical case reports · 2023Review
- Article
- Ber-EP4 staining patterns on basal cell carcinomas.Northern clinics of Istanbul · 2023Article
- Shedding light on the EpCAM: An overview.Journal of cellular physiology · 2019Review
- Applications of SNAP-tag technology in skin cancer therapy.Health science reports · 2019Review
- Role of p16 deletion and BAP1 loss in the diagnosis of malignant mesothelioma.Journal of thoracic disease · 2018Article
- EpCAM Expression in Lymph Node Metastases of Urothelial Cell Carcinoma of the Bladder: A Pilot Study.International journal of molecular sciences · 2017Article
- Article
- Breast carcinoma masquerading as basal cell carcinoma of the nipple.JAAD case reports · 2015Article
- Phenotypic and in vivo functional characterization of immortalized human fetal liver cells.Scandinavian journal of gastroenterology · 2014Article
- Expanding the clinical phenotype of hereditary BAP1 cancer predisposition syndrome, reporting three new cases.Genes, chromosomes & cancer · 2014Article
- Is minimal residual lymph node disease in papillary thyroid cancer of prognostic impact? An analysis of the epithelial cell adhesion molecule EpCAM in lymph nodes of 40 pN0 patients.Pathology oncology research : POR · 2014Article
- Intraoral basal cell carcinoma, a rare neoplasm: report of three new cases with literature review.Head and neck pathology · 2014Review
- Use of Ber-EP4 and Epithelial Specific Antigen to Differentiate Clinical Simulators of Basal Cell Carcinoma.Biomarkers in cancer · 2013Article
- Isolation and characterization of intestinal epithelial cells from normal and SIV-infected rhesus macaques.PloS one · 2012Article
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new monoclonal antibody, Ber-EP4, directed against a partially formol resistant epitope on the protein moiety of two 34 kilodalton and 39 kilodalton glycopolypeptides on human epithelial cells is described. Immunostaining of a wide range of normal and neoplastic human tissues and cell lines showed that all carcinomas and all non-neoplastic epithelial cells, except hepatocytes, parietal cells, and apical cell layers in squamous epithelia, homogeneously expressed Ber-EP4 antigen. As Ber-EP4 does not detect any normal or neoplastic non-epithelial cells, this antibody might prove valuable for the differentiation of the following (i) non-epithelial tumours from undifferentiated carcinomas; (ii) hepatocytes from bile duct cells in certain liver diseases; (iii) mesothelial cells from carcinoma cells in lung biopsy specimens; and (iv) reactive mesothelial cells from carcinoma cells in smears of serous effusions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.