Evidence map›Paper›PMID 16919437›Full record

ReviewCurrent opinion in cell biology2006

CEACAMs: their role in physiology and pathophysiology.

Katharina Kuespert, Stefan Pils, Christof R Hauck

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 204 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
204citing papers in PubMed, 2 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

204 citing papers in PubMed, 2 syntheses or guidelines pooled it, 394 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
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  11. Review
  12. Article
  13. Article
  14. Exploring the interactions of integrins and CEACAM6 (Review).Experimental and therapeutic medicine · 2025
    Review
  15. Proteomic Exploration of L1CAMInternational journal of molecular sciences · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Effects of the gut microbiota on placental angiogenesis and intrauterine growth in gnotobiotic mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article

144 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katharina KuespertLehrstuhl Zellbiologie, Fachbereich Biologie X908, Universität Konstanz, Universitätsstrasse 10, 78457 Konstanz, Germany.
Stefan Pils
Christof R Hauck
University of Konstanz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin-related glycoproteins. They are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation. CEACAMs have also been identified as receptors for host-specific viruses and bacteria in mice and humans, respectively, making these proteins an interesting example of pathogen-host co-evolution. Forward and reverse genetics in the mouse now provide powerful novel models to elucidate the action of CEACAM family members in vivo.

Indexed as

AnimalsAnimals, Genetically ModifiedAntigens, CDBacteriaCarcinoembryonic AntigenCell Adhesion MoleculesEvolution, MolecularHumansInsulinNeoplasmsNeovascularization, PhysiologicProtein IsoformsVirusesAntigens, CDCarcinoembryonic AntigenCD66 antigensCEACAM3 protein, humanCell Adhesion MoleculesInsulinProtein Isoforms

Identifiers

PMID16919437
PMCPMC7127089
OpenAlexW2149865188

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.