Evidence map›Paper›PMID 16919436›Full record

ReviewCurrent opinion in cell biology2006

Interdependence of cell attachment and cell cycle signaling.

Elena N Pugacheva, Fabrice Roegiers, Erica A Golemis

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 62 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds.Frontiers in bioengineering and biotechnology · 2021
    Article
  12. Review
  13. Review
  14. Article
  15. Division-independent differentiation mandates proliferative competition among stem cells.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  16. Review
  17. Article
  18. Article
  19. Nedd9 restrains renal cystogenesis in Pkd1-/- mice.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Elena N PugachevaDivision of Basic Science, Fox Chase Cancer Center, 333 Cottman Ave. Philadelphia, PA 19111, USA.
Fabrice Roegiers
Erica A Golemis
Fox Chase Cancer Center · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
ROLES OF HEF1 IN CELL DIFFERENTIATION AND SURVIVALR01CA063366 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI GOLEMIS, ERICA A. · 1998 to 2013
$3.9M
CONTROL OF NORMAL AND ABNORMAL CELL GROWTHR29CA063366 · NCI · INSTITUTE FOR CANCER RESEARCH · PI GOLEMIS, ERICA A · 1994 to 1997
–
NCI NIH HHS CA-06927NCI NIH HHS CA63366NCI NIH HHS P30 CA006927NCI NIH HHS R01 CA063366
6 · The paper itself

Abstract

Adult metazoans represent the culmination of an intricate developmental process involving the temporally and spatially orchestrated division, migration, differentiation, attachment, polarization and death of individual cells. An elaborate infrastructure connecting the cell cycle and cell attachment machinery is essential for such exquisite integration of developmental processes. Integrin-, cadherin-, Merlin- and planar cell polarity (PCP)-dependent signaling cascades quantitatively and qualitatively program cell division during development. Proteins in this signaling infrastructure may represent an important source of cancer vulnerability in metazoans, as their dysfunction can pleiotropically promote the oncogenic process.

Indexed as

AnimalsCadherinsCell AdhesionCell CycleIntegrinsNeurofibromin 2Signal TransductionCadherinsIntegrinsNeurofibromin 2

Identifiers

PMID16919436
PMCPMC2531247
OpenAlexW1999768740

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.