ArticleBiochemical and biophysical research communications2006
Search for basonuclin target genes.
Article in Biochemical and biophysical research communications, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 31 citations in OpenAlex.
- BNC1 Promotes Spermatogenesis by Regulating Transcription of Ybx2 and Papolb via Direct Binding to Their Promotor Elements.Reproductive sciences (Thousand Oaks, Calif.) · 2021Article
- The p53 family reaches the final frontier: the variegated regulation of the dark matter of the genome by the p53 family in cancer.RNA biology · 2020Article
- Basonuclin 1 deficiency causes testicular premature aging: BNC1 cooperates with TAF7L to regulate spermatogenesis.Journal of molecular cell biology · 2020Article
- DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling.Oncogene · 2017Article
- Article
- Basonuclin-1 modulates epithelial plasticity and TGF-β1-induced loss of epithelial cell integrity.Oncogene · 2015Article
- The GALNT9, BNC1 and CCDC8 genes are frequently epigenetically dysregulated in breast tumours that metastasise to the brain.Clinical epigenetics · 2015Article
- Novel methylation biomarker panel for the early detection of pancreatic cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013Article
- Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus.BMC immunology · 2013Article
- BNC1 is required for maintaining mouse spermatogenesis.Genesis (New York, N.Y. : 2000) · 2012Article
- GWASdb: a database for human genetic variants identified by genome-wide association studies.Nucleic acids research · 2012Article
- ChIP-Array: combinatory analysis of ChIP-seq/chip and microarray gene expression data to discover direct/indirect targets of a transcription factor.Nucleic acids research · 2011Article
- Human balanced translocation and mouse gene inactivation implicate Basonuclin 2 in distal urethral development.European journal of human genetics : EJHG · 2011Article
- An SNP selection strategy identified IL-22 associating with susceptibility to tuberculosis in Chinese.Scientific reports · 2011Article
- Identification of candidate tumour suppressor genes frequently methylated in renal cell carcinoma.Oncogene · 2010Article
- Basonuclin-2 requirements for zebrafish adult pigment pattern development and female fertility.PLoS genetics · 2009Article
- PU.1 can recruit BCL6 to DNA to repress gene expression in germinal center B cells.Molecular and cellular biology · 2009Article
- Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Basonuclin-null mutation impairs homeostasis and wound repair in mouse corneal epithelium.PloS one · 2007Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Basonuclin (Bnc 1) is a transcription factor that has an unusual ability to interact with promoters of both RNA polymerases I and II. The action of basonuclin is mediated through three pairs of evolutionarily conserved zinc fingers, which produce three DNase I footprints on the promoters of rDNA and the basonuclin gene. Using these DNase footprints, we built a computational model for the basonuclin DNA-binding module, which was used to identify in silico potential RNA polymerase II target genes in the human and mouse promoter databases. The target genes of basonuclin show that it regulates the expression of proteins involved in chromatin structure, transcription/DNA-binding, ion-channels, adhesion/cell-cell junction, signal transduction, and intracellular transport. Our results suggest that basonuclin, like MYC, may coordinate transcriptional activities among the three RNA polymerases. But basonuclin regulates a distinctive set of pathways, which differ from that regulated by MYC.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.