ArticleThe Journal of physiology2006
Change in contractile properties of human muscle in relationship to the loss of power and slowing of relaxation seen with fatigue.
Article in The Journal of physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Muscle contractile properties of cancer patients receiving chemotherapy: Assessment of feasibility and exercise effects.Scandinavian journal of medicine & science in sports · 2020Trial
- β-alanine supplementation improves in-vivo fresh and fatigued skeletal muscle relaxation speed.European journal of applied physiology · 2017Trial
- Cumulative effects of HThe Journal of physiology · 2025Article
- Exploring the torque- velocity relationship in postmenopausal women: Analyzing the influence of data processing.PloS one · 2025Article
- Understanding altered contractile properties in advanced age: insights from a systematic muscle modelling approach.Biomechanics and modeling in mechanobiology · 2023Article
- Article
- Comparison of prolonged low-frequency force depression assessed using isometric torque and isotonic power following a dynamic fatiguing task.European journal of applied physiology · 2022Article
- Molecular Events of the Crossbridge Cycle Reflected in the Force-Velocity Relationship of Activated Muscle.Frontiers in physiology · 2022Review
- Maximal muscular power: lessons from sprint cycling.Sports medicine - open · 2021Review
- Changes in electromyographic activity, mechanical power, and relaxation rates following inspiratory ribcage muscle fatigue.Scientific reports · 2021Observational
- Are Force Enhancement after Stretch and Muscle Fatigue Due to Effects of Elevated Inorganic Phosphate and Low Calcium on Cross Bridge Kinetics?Medicina (Kaunas, Lithuania) · 2020Article
- Is curvature of the force-velocity relationship affected by oxygen availability? Evidence from studies in ex vivo and in situ rat muscles.Pflugers Archiv : European journal of physiology · 2020Article
- Differential contributions of fatigue-induced strength loss and slowing of angular velocity to power loss following repeated maximal shortening contractions.Physiological reports · 2020Article
- Voluntary and electrically-induced muscle fatigue differently affect postural control mechanisms in unipedal stance.Experimental brain research · 2019Article
- Effects of elevated HThe Journal of physiology · 2018Article
- Model-based analysis of fatigued human knee extensors : Effects of isometrically induced fatigue on Hill-type model parameters and ballistic contractions.European journal of applied physiology · 2018Article
- Older men are more fatigable than young when matched for maximal power and knee extension angular velocity is unconstrained.Age (Dordrecht, Netherlands) · 2015Article
- Reducing muscle fatigue during transcutaneous neuromuscular electrical stimulation by spatially and sequentially distributing electrical stimulation sources.European journal of applied physiology · 2014Article
- Hill's equation of muscle performance and its hidden insight on molecular mechanisms.The Journal of general physiology · 2013Review
- Effect of old age on human skeletal muscle force-velocity and fatigue properties.Journal of applied physiology (Bethesda, Md. : 1985) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Slow relaxation from an isometric contraction is characteristic of acutely fatigued muscle and is associated with a decrease in the maximum velocity of unloaded shortening (V(max)) and both these phenomena might be due to a decreased rate of cross bridge detachment. We have compared the change in relaxation rate with that of various parameters of the force-velocity relationship over the course of an ischaemic series of fatiguing contractions and subsequent recovery using the human adductor pollicis muscle working in vivo at approximately 37 degrees C in nine healthy young subjects. Maximal isometric force (F(0)) decreased from 91.0 +/- 1.9 to 58.3 +/- 3.5 N (mean +/- s.e.m.). Maximum power decreased from 53.6 +/- 4.0 to 17.7 +/- 1.2 (arbitrary units) while relaxation rate declined from -10.3 +/- 0.38 to -2.56 +/- 0.29 s(-1). V(max) showed a smaller relative change from 673 +/- 20 to 560 +/- 46 deg s(-1) and with a time course that differed markedly from that of slowing of relaxation, showing very little change until late in the series of contractions. Curvature of the force-velocity relationship increased (a/F(0) decreasing from 0.22 +/- 0.02 to 0.11 +/- 0.02) with fatigue and with a time course that was similar to that of the loss of power and the slowing of relaxation. It is concluded that for human muscle working at a normal physiological temperature the change in curvature of the force-velocity relationship with fatigue is a major cause of loss of power and may share a common underlying mechanism with the slowing of relaxation from an isometric contraction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.