ArticlePlant molecular biology2006
Rice Chlorina-1 and Chlorina-9 encode ChlD and ChlI subunits of Mg-chelatase, a key enzyme for chlorophyll synthesis and chloroplast development.
Article in Plant molecular biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.
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121 citing papers in PubMed, 288 citations in OpenAlex.
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- Identification of photosynthetic pigment content-related genes in peanut (Arachis hypogaea L.) by GWAS and RNA-seq.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Deletion of the gene encoding the magnesium chelatase I subunit resulted in a novel wheat leaf colour mutant.Plant biotechnology journal · 2025Article
- Genome-Wide Characterization of the Von Willebrand Factor a Gene Family in Wheat: Highlights Their Functional Roles in Growth and Biotic Stress Response.Plants (Basel, Switzerland) · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
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- Genome-wide identification and functional analysis of PEL gene family in Brassica napus L.BMC plant biology · 2025Article
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- Mechanism of Penoxsulam's Effect on Chlorophyll Synthesis and the Metabolism of Foxtail Millet.Plants (Basel, Switzerland) · 2025Article
- Barley young leaf chlorina, a putative pentatricopeptide repeat gene, is essential for chloroplast development in young leaves.Plant molecular biology · 2025Article
- The SUMO-conjugating enzyme OsSCE1a from wild rice regulates the functional stay-green trait in rice.Plant biotechnology journal · 2025Article
- Insight into the genetics of a novel white-striped leaf in rice.Frontiers in plant science · 2025Article
- Revealing the key role of the folate synthesis regulatory gene DHNA in tobacco leaf yellowing based on BSA-seq, RNA-seq, and proteomic sequencing.BMC plant biology · 2024Article
- A missense mutation in the barley Xan-h gene encoding the Mg-chelatase subunit I leads to a viable pale green line with reduced daily transpiration rate.Plant cell reports · 2024Article
- Conjunctive BSA-Seq and BSR-Seq to Map the Genes of Yellow Leaf Mutations in Hot Peppers (Genes · 2024Article
- Deletion of the sugar importer gene OsSWEET1b accelerates sugar starvation-promoted leaf senescence in rice.Plant physiology · 2024Article
61 more citing papers are in PubMed but not listed here.
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8 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Photosynthetic organisms exhibit a green color due to the accumulation of chlorophyll pigments in chloroplasts. Mg-protoporphyrin IX chelatase (Mg-chelatase) comprises three subunits (ChlH, ChlD and ChlI) and catalyzes the insertion of Mg(2+) into protoporphyrin IX, the last common intermediate precursor in both chlorophyll and heme biosyntheses, to produce Mg-protoporphyrin IX (MgProto). Chlorophyll deficiency in higher plants results in chlorina (yellowish-green) phenotype. To date, 10 chlorina (chl) mutants have been isolated in rice, but the corresponding genes have not yet been identified. Rice Chl1 and Chl9 genes were mapped to chromosome 3 and isolated by map-based cloning. A missense mutation occurred in a highly conserved amino acid of ChlD in the chl1 mutant and ChlI in the chl9 mutant. Ultrastructural analyses have revealed that the grana are poorly stacked, resulting in the underdevelopment of chloroplasts. In the seedlings fed with aminolevulinate-dipyridyl in darkness, MgProto levels in the chl1 and chl9 mutants decreased up to 25% and 31% of that in wild-type, respectively, indicating that the Mg-chelatase activity is significantly reduced, causing the eventual decrease in chlorophyll synthesis. Furthermore, Northern blot analysis indicated that the nuclear genes encoding the three subunits of Mg-chelatase and LhcpII in chl1 mutant are expressed about 2-fold higher than those in WT, but are not altered in the chl9 mutant. This result indicates that the ChlD subunit participates in negative feedback regulation of plastid-to-nucleus in the expression of nuclear genes encoding chloroplast proteins, but not the ChlI subunit.
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