Evidence map›Paper›PMID 16908667›Full record

ReviewThe Journal of cell biology2006

Phosphoinositide signaling plays a key role in cytokinesis.

Chris Janetopoulos, Peter Devreotes

Open access · bronzeAbstract readReview
In one paragraph

Review in The Journal of cell biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 105 citations in OpenAlex.

  1. Article
  2. Signaling and actin waves at a glance.Journal of cell science · 2025
    Review
  3. Lysosomal PIPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Review
  6. Article
  7. Gradients of PI(4,5)PFrontiers in cell and developmental biology · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Rab GTPases and cell division.Small GTPases · 2018
    Review
  15. Coupling changes in cell shape to chromosome segregation.Nature reviews. Molecular cell biology · 2016
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Chris JanetopoulosDepartment of Biological Sciences, Vanderbilt University, Nashville, TN 37232, USA.
Peter Devreotes
Johns Hopkins University · USVanderbilt University · US

Funding

SIGNAL TRANSDUCTION AND DICTYOSTELIUM DEVELOPMENTR01GM028007 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI DEVREOTES, PETER N · 1985 to 2004
$2.4M
NIGMS NIH HHS R01 GM028007
6 · The paper itself

Abstract

To perform the vital functions of motility and division, cells must undergo dramatic shifts in cell polarity. Recent evidence suggests that polarized distributions of phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate, which are clearly important for regulating cell morphology during migration, also play an important role during the final event in cell division, which is cytokinesis. Thus, there is a critical interplay between the membrane phosphoinositides and the cytoskeletal cortex that regulates the complex series of cell shape changes that accompany these two processes.

Indexed as

AnimalsCell PolarityCell ShapeCytokinesisCytoskeletonHumansPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositolsSignal Transductionphosphatidylinositol 3,4,5-triphosphatePhosphatidylinositol 4,5-DiphosphatePhosphatidylinositol PhosphatesPhosphatidylinositols

Identifiers

PMID16908667
PMCPMC2064254
OpenAlexW2142918956

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.