ArticleMolecular and cellular biology1990
Regulation of expression of growth arrest-specific genes in mouse fibroblasts.
Article in Molecular and cellular biology, 1990. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Tumor Suppressive Effects of GAS5 in Cancer Cells.Non-coding RNA · 2022Review
- Growth arrest-specific 2 protein family: Structure and function.Cell proliferation · 2021Review
- Stressing out over long noncoding RNA.Biochimica et biophysica acta · 2016Review
- Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity.Cell cycle (Georgetown, Tex.) · 2012Article
- Age- and cell cycle-dependent changes in EPC-1/PEDF promoter activity in human diploid fibroblast-like (HDF) cells.Molecular and cellular biochemistry · 2006Article
- SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis.BMC cancer · 2006Article
- Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes.Molecular and cellular biology · 1998Article
- A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy.Nucleic acids research · 1998Article
- Myc represses transcription of the growth arrest gene gas1.Proceedings of the National Academy of Sciences of the United States of America · 1997Article
- Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest.The Journal of biological chemistry · 1996Article
- Transcriptional stimulation of the retina-specific QR1 gene upon growth arrest involves a Maf-related protein.Molecular and cellular biology · 1995Article
- The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.Molecular and cellular biology · 1994Article
- Posttranscriptional down-regulation of ras oncogene expression by inhibitors of cellular glutathione.Molecular and cellular biology · 1993Article
- Molecular cloning of a diverged homeobox gene that is rapidly down-regulated during the G0/G1 transition in vascular smooth muscle cells.Molecular and cellular biology · 1993Article
- Regulation and expression of a growth arrest-specific gene (gas5) during growth, differentiation, and development.Molecular and cellular biology · 1992Article
- Expression of a growth arrest specific gene (gas-1) in transformed cells.British journal of cancer · 1992Article
- Growth-regulated expression of rhoG, a new member of the ras homolog gene family.Molecular and cellular biology · 1992Article
- Characterization of a novel peripheral nervous system myelin protein (PMP-22/SR13).The Journal of cell biology · 1992Article
- Axon-regulated expression of a Schwann cell transcript that is homologous to a 'growth arrest-specific' gene.The EMBO journal · 1991Article
- Cloning of a growth arrest-specific and transforming growth factor beta-regulated gene, TI 1, from an epithelial cell line.Molecular and cellular biology · 1991Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The suppression of growth arrest-specific (gas) gene expression by serum appeared to be independent of protein synthesis, but expression in resting cells was sensitive to 2-aminopurine, an inhibitor of intracellular protein kinases. Although accumulation of gas gene mRNA was reduced by serum, nuclear transcription of the gas-2, -3, and -5 genes was observed in serum-stimulated cells, indicating that posttranscriptional events may regulate mRNA levels. Growth induction by serum, on the other hand, led to suppression of transcription of the gas-1 gene. Cell cycle regulation and the serum response of gas-1 were lost in ras-transformed cells.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.