ArticleThe Plant cell2006
Biz1, a zinc finger protein required for plant invasion by Ustilago maydis, regulates the levels of a mitotic cyclin.
Article in The Plant cell, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed, 83 citations in OpenAlex.
- Combinatorial cis-regulatory elements shape temporal effector expression in Ustilago maydis.Molecular plant pathology · 2026Article
- The cell cycle, autophagy, and cell wall integrity pathway jointly governed by MoSwe1 in Magnaporthe oryzae.Cell communication and signaling : CCS · 2024Article
- Identification of a CJournal of fungi (Basel, Switzerland) · 2022Article
- Incompatibility between proliferation and plant invasion is mediated by a regulator of appressorium formation in the corn smut fungusProceedings of the National Academy of Sciences of the United States of America · 2020Article
- An Ustilago maydis chassis for itaconic acid production without by-products.Microbial biotechnology · 2020Article
- Article
- N-glycosylation of the protein disulfide isomerase Pdi1 ensures full Ustilago maydis virulence.PLoS pathogens · 2019Article
- Cytoplasmic retention and degradation of a mitotic inducer enable plant infection by a pathogenic fungus.eLife · 2019Article
- Modulation of lipid content and lipid profile by supplementation of iron, zinc, and molybdenum in indigenous microalgae.Environmental science and pollution research international · 2019Article
- Deletion ofJournal of fungi (Basel, Switzerland) · 2018Article
- Fungal Morphogenesis, from the Polarized Growth of Hyphae to Complex Reproduction and Infection Structures.Microbiology and molecular biology reviews : MMBR · 2018Review
- The Biotrophic Development ofThe Plant cell · 2018Article
- Online evaluation of the metabolic activity ofJournal of biological engineering · 2018Article
- Transcripts and tumors: regulatory and metabolic programming during biotrophic phytopathogenesis.F1000Research · 2018Review
- Ustilago maydis effectors and their impact on virulence.Nature reviews. Microbiology · 2017Review
- Promoters from the itaconate cluster ofFungal biology and biotechnology · 2017Article
- Characterization of ApB73, a virulence factor important for colonization of Zea mays by the smut Ustilago maydis.Molecular plant pathology · 2016Article
- Activating Intrinsic Carbohydrate-Active Enzymes of the Smut Fungus Ustilago maydis for the Degradation of Plant Cell Wall Components.Applied and environmental microbiology · 2016Article
- The WOPR Protein Ros1 Is a Master Regulator of Sporogenesis and Late Effector Gene Expression in the Maize Pathogen Ustilago maydis.PLoS pathogens · 2016Article
- Unfolded Protein Response (UPR) Regulator Cib1 Controls Expression of Genes Encoding Secreted Virulence Factors in Ustilago maydis.PloS one · 2016Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant invasion by pathogenic fungi involves regulated growth and highly organized fungal morphological changes. For instance, when the smut fungus Ustilago maydis infects maize (Zea mays), its dikaryotic infective filament is cell cycle arrested, and appressoria are differentiated prior to plant penetration. Once the filament enters the plant, the cell cycle block is released and fungal cells begin proliferation, suggesting a tight interaction between plant invasion and the cell cycle and morphogenesis control systems. We describe a novel factor, Biz1 (b-dependent zinc finger protein), which has two Cys(2)His(2) zinc finger domains and nuclear localization, suggesting a transcriptional regulatory function. The deletion of biz1 shows no detectable phenotypic alterations during axenic growth. However, mutant cells show a severe reduction in appressoria formation and plant penetration, and those hyphae that invade the plant arrest their pathogenic development directly after plant penetration. biz1 is induced via the b-mating-type locus, the key control instance for pathogenic development. The gene is expressed at high levels throughout pathogenic development, which induces a G2 cell cycle arrest that is a direct consequence of the downregulation of the mitotic cyclin Clb1. Our data support a model in which Biz1 is involved in cell cycle arrest preceding plant penetration as well as in the induction of appressoria.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.