Evidence map›Paper›PMID 16905634›Full record

SynthesisSchizophrenia bulletin2006

Efficacy of psychological therapy in schizophrenia: conclusions from meta-analyses.

Mario Pfammatter, Ulrich Martin Junghan, Hans Dieter Brenner

Registry-linked trialOpen access · bronzeAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Schizophrenia bulletin, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01055509 (Effectiveness of Cognitive Adaptation Training Applied to Cognitive Impairment in Schizophrenia - A Randomised Trial), which is not on this map. Cited by 100 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
100citing papers in PubMed, 11 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01055509 nacompletednot on this mapstarted 2009, after this paper: background citation

Effectiveness of Cognitive Adaptation Training Applied to Cognitive Impairment in Schizophrenia - A Randomised Trial

TypeinterventionalSponsorUniversity of Southern DenmarkRan2009 to 2011Enrolled65ConditionsSchizophreniaArmsCognitive Adaptation Training
3 · Its place in the literature

Who cites it

100 citing papers in PubMed, 11 syntheses or guidelines pooled it, 391 citations in OpenAlex.

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  5. S3 guideline on psychosocial therapies in severe mental illness: evidence and recommendations.European archives of psychiatry and clinical neuroscience · 2015
    Guideline
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  14. How does family intervention improve the outcome of people with schizophrenia?Social psychiatry and psychiatric epidemiology · 2015
    Trial
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40 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mario PfammatterDepartment of Psychotherapy, University Hospital of Psychiatry, Laupenstrasse 49, CH-3010 Bern, Switzerland. mario.pfammatter@spk.unibe.ch
Ulrich Martin Junghan
Hans Dieter Brenner
Universidad Iberoamericana · DO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the past years, evidence for the efficacy of psychological therapies in schizophrenia has been summarized in a series of meta-analyses. The present contribution aims to provide a descriptive survey of the evidence for the efficacy of psychological therapies as derived from these meta-analyses and to supplement them by selected findings from an own recent meta-analysis. Relevant meta-analyses and randomized controlled trials were identified by searching several electronic databases and by hand searching of reference lists. In order to compare the findings of the existing meta-analyses, the reported effect sizes were extracted and transformed into a uniform effect size measure where possible. For the own meta-analysis, weighted mean effect size differences between comparison groups regarding various types of outcomes were estimated. Their significance was tested by confidence intervals, and heterogeneity tests were applied to examine the consistency of the effects. From the available meta-analyses, social skills training, cognitive remediation, psychoeducational coping-oriented interventions with families and relatives, as well as cognitive behavioral therapy of persistent positive symptoms emerge as effective adjuncts to pharmacotherapy. Social skills training consistently effectuates the acquisition of social skills, cognitive remediation leads to short-term improvements in cognitive functioning, family interventions decrease relapse and hospitalization rates, and cognitive behavioral therapy results in a reduction of positive symptoms. These benefits seem to be accompanied by slight improvements in social functioning. However, open questions remain as to the specific therapeutic ingredients, to the synergistic effects, to the indication, as well as to the generalizability of the findings to routine care.

Indexed as

Cognitive Behavioral TherapyHumansSchizophreniaSocial BehaviorTeachingTreatment Outcome

Identifiers

PMID16905634
PMCPMC2632545
OpenAlexW2122479416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.