ArticleHeart (British Cardiac Society)2007
Oral glucose tolerance test is needed for appropriate classification of glucose regulation in patients with coronary artery disease: a report from the Euro Heart Survey on Diabetes and the Heart.
Article in Heart (British Cardiac Society), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 137 citations in OpenAlex.
- Effects of Extended-Release Niacin Added to Simvastatin/Ezetimibe on Glucose and Insulin Values in AIM-HIGH.The American journal of medicine · 2016Trial
- Prevalence of undiagnosed abnormal glucose tolerance in adult patients cared for by general practitioners in Hungary. Results of a risk-stratified screening based on FINDRISC questionnaire.Medical science monitor : international medical journal of experimental and clinical research · 2013Trial
- Relative utility of 1-h Oral Glucose Tolerance Test as a measure of abnormal glucose homeostasis.Diabetes research and clinical practice · 2011Trial
- Diagnosis of diabetes without oral glucose tolerance test is associated with increased mortality in older adults.Scientific reports · 2025Article
- Evidence of a bi-directional relationship between heart failure and diabetes: a strategy for the detection of glucose abnormalities and diabetes prevention in patients with heart failure.Cardiovascular diabetology · 2024Review
- Prognostic Value of Serum 1,5-anhydroglucitol Levels in Patients with Acute Myocardial Infarction.Reviews in cardiovascular medicine · 2022Article
- Article
- HbA1c Screening for Diabetes in Patients with Acute Coronary Syndrome: A Worthwhile Test or a Pitfall?Journal of clinical medicine · 2021Article
- Hemoglobin A1c in Patients with Diabetes Predict Long-Term Mortality Following Coronary Artery Surgery.Journal of clinical medicine · 2021Article
- Long-term prognosis in patients with acute myocardial infarction and newly detected glucose abnormalities: predictive value of oral glucose tolerance test and HbA1c.Cardiovascular diabetology · 2021Observational
- Incidence of cardiovascular events in patients with stabilized coronary heart disease: the EUROASPIRE IV follow-up study.European journal of epidemiology · 2019Article
- ANMCO/GICR-IACPR/SICI-GISE Consensus Document: the clinical management of chronic ischaemic cardiomyopathy.European heart journal supplements : journal of the European Society of Cardiology · 2017Article
- Detecting prediabetes among Hispanics/Latinos from diverse heritage groups: Does the test matter? Findings from the Hispanic Community Health Study/Study of Latinos.Preventive medicine · 2017Article
- HbAJournal of diabetes and metabolic disorders · 2017Article
- Management standards for stable coronary artery disease in India.Indian heart journal · 2016Review
- Ryanodine receptor phosphorylation by CaMKII promotes spontaneous Ca(2+) release events in a rodent model of early stage diabetes: The arrhythmogenic substrate.International journal of cardiology · 2016Article
- Recognition of incident diabetes mellitus during an acute myocardial infarction.Circulation. Cardiovascular quality and outcomes · 2015Article
- Prevalence of glucose abnormalities among patients presenting with an acute myocardial infarction.American heart journal · 2014Article
- The reliability of in-hospital diagnoses of diabetes mellitus in the setting of an acute myocardial infarction.BMJ open diabetes research & care · 2014Article
- The association between self-reported lack of sleep, low vitality and impaired glucose tolerance: a Swedish cross-sectional study.BMC public health · 2013Article
Corrections and comments
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Authors and funding
10 authors at 7 institutions in 7 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with coronary artery disease (CAD) and abnormal glucose regulation (AGR) are at high risk for subsequent cardiovascular events, underlining the importance of accurate glucometabolic assessment in clinical practice.
objectiveTo investigate different methods to identify glucose disturbances among patients with acute and stable coronary heart disease.
methodsConsecutive patients referred to cardiologists were prospectively enrolled at 110 centres in 25 countries (n = 4961). Fasting plasma glucose (FPG) and glycaemia 2 h after a 75-g glucose load were requested in patients without known glucose abnormalities (n = 3362). Glucose metabolism was classified according to the World Health Organization and American Diabetes Association (ADA; 1997, 2004) criteria as normal, impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or diabetes.
resultsData on FPG and 2-h post-load glycaemia were available for 1867 patients, of whom 870 (47%) had normal glucose regulation, 87 (5%) had IFG, 591 (32%) had IGT and 319 (17%) had diabetes. If classification had been based on the ADA criterion from 1997, the proportion of misclassified (underdiagnosed) patients would have been 39%. The ADA 2004 criterion would have overdiagnosed 8% and underdiagnosed 33% of the patients, resulting in a total misclassification rate of 41%. For ethical concerns and practical reasons, oral glucose tolerance test (OGTT) was not conducted in 1495 of eligible patients. These patients were more often women, had higher age and waist circumference, and were therefore more likely to have AGR than those who were included. A model based on easily available clinical and laboratory variables, including FPG, high-density lipoprotein cholesterol, age and the logarithm of glycated haemoglobin A1c, misclassified 44% of the patients, of whom 18% were overdiagnosed and 26% were underdiagnosed.
conclusionAn OGTT is still the most appropriate method for the clinical assessment of glucometabolic status in patients with coronary heart disease.
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