Evidence map›Paper›PMID 16905562›Full record

ArticleArchives of disease in childhood2007

Effect of a clinical pathway on the hospitalisation rates of children with asthma: a prospective study.

S P Norton, M V Pusic, F Taha, S Heathcote, B C Carleton

Abstract readControlled Clinical Trial
In one paragraph

Article in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Clinical pathways for chronic cough in children.The Cochrane database of systematic reviews · 2014
    Pooled it
  2. A systematic review of the implementation and impact of asthma protocols.BMC medical informatics and decision making · 2014
    Pooled it
  3. Impact of a standardized emergency department asthma care pathway on health services utilization.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2025
    Article
  4. Article
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  6. Review
  7. Article
  8. A Primer on Clinical Pathways.Hospital pharmacy · 2016
    Article
  9. Article
  10. Article
  11. Asthma-related emergency department use: current perspectives.Open access emergency medicine : OAEM · 2016
    Review
  12. Article
  13. Article
  14. Clinical pathway improves pediatrics asthma management in the emergency department and reduces admissions.The Journal of asthma : official journal of the Association for the Care of Asthma · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

S P NortonDepartment of Pediatrics, British Columbia's Children's Hospital, University of British Columbia, Vancouver, British Columbia, Canada. spnorton@hotmail.com
M V Pusic
F Taha
S Heathcote
B C Carleton

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the effect of implementing a clinical pathway, using evidence-based clinical practice guidelines, for the emergency care of children and adolescents with asthma.

methodsA prospective, before-after, controlled trial was conducted, which included patients aged 1-18 years who had acute exacerbations of asthma treated in a tertiary care paediatric emergency department. Data were collected for identical 2-month seasonal periods before and after implementation of the clinical pathway to determine hospitalisation rate and other outcomes. For 2 weeks after emergency visits, the rate at which patients returned to emergency care for worsening asthma was evaluated. A multidisciplinary panel, using national guidelines and a systematic review, developed the pathway.

results267 patients were studied. The rate of hospitalisation was significantly lower in the post-implementation group (10/74; 13.5%) than in the pre-implementation control group (53/193; 27.5%; p = 0.02; number needed to treat 7.1). All reduction in hospitalisation occurred in children with moderate to severe asthma exacerbation. After implementation of the clinical pathway, the rate of administration of oral corticosteroids to patients with moderate or severe exacerbations increased from 71% to 92% (p = 0.01), and significantly more patients received beta2-agonists in the first hour (p = 0.02). No significant change in relapse to acute care occurred within 2 weeks (p = 0.19).

conclusionsAn evidence-based clinical pathway for children and adolescents with moderate to severe exacerbations of acute asthma markedly decreases their rate of hospitalisation without increased return to emergency care.

Indexed as

Bronchodilator AgentsAcute DiseaseAdministration, InhalationAdolescentAdrenal Cortex HormonesAsthmaChildChild, PreschoolCritical PathwaysEmergency Service, HospitalEvidence-Based MedicineFemaleHospitalizationHumansInfantMaleAdrenal Cortex HormonesBronchodilator Agents

Identifiers

PMID16905562
PMCPMC2083153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.