ReviewTrends in parasitology2006
Toxoplasma gondii and subversion of the immune system.
Review in Trends in parasitology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Neuronal responses to cytokines limit intestinal hypermotility and systemic effects of colonic inflammation.iScience · 2026Article
- Retinal pigment epithelium drives macrophage migration during Toxoplasma gondii infection in vitroMemorias do Instituto Oswaldo Cruz · 2026Article
- SIRT1 Promotes Host Protective Immunity againstInternational journal of molecular sciences · 2022Article
- Antibiotic Changes Host Susceptibility to Eimeria falciformis Infection Associated with Alteration of Gut Microbiota.Infection and immunity · 2022Article
- High resistance toiScience · 2021Article
- Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization.PLoS neglected tropical diseases · 2021Article
- Microneme Proteins 1 and 4 FromFrontiers in immunology · 2021Article
- Catastrophic consequences: can the feline parasite Toxoplasma gondii prompt the purrfect neuroinflammatory storm following traumatic brain injury?Journal of neuroinflammation · 2020Review
- From Entry to Early Dissemination-Frontiers in cellular and infection microbiology · 2019Review
- Inherent Oxidative Stress in the Lewis Rat Is Associated with Resistance to Toxoplasmosis.Infection and immunity · 2017Article
- Innate recognition of Toxoplasma gondii in humans involves a mechanism distinct from that utilized by rodents.Cellular & molecular immunology · 2017Review
- SAG2A protein from Toxoplasma gondii interacts with both innate and adaptive immune compartments of infected hosts.Parasites & vectors · 2013Article
- Intraepithelial lymphocytes, goblet cells and VIP-IR submucosal neurons of jejunum rats infected with Toxoplasma gondii.International journal of experimental pathology · 2012Article
- Macrophage migration inhibitory factor in protozoan infections.Journal of parasitology research · 2012Article
- Programmed death ligand 2 regulates arginase induction and modifies Trypanosoma cruzi survival in macrophages during murine experimental infection.Immunology · 2011Article
- Suppression of CD4 T-Cells in the spleen of mice infected with Toxoplasma gondii KI-1 tachyzoites.The Korean journal of parasitology · 2010Article
- Suppressed production of pro-inflammatory cytokines by LPS-activated macrophages after treatment with Toxoplasma gondii lysate.The Korean journal of parasitology · 2008Article
- Are some cases of psychosis caused by microbial agents? A review of the evidence.Molecular psychiatry · 2008Review
- Anisakis simplex: from obscure infectious worm to inducer of immune hypersensitivity.Clinical microbiology reviews · 2008Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Toxoplasma gondii is an intracellular obligate parasite that enters the host via the gastrointestinal tract. The parasite is able to evade or subvert the immune response of its host via various mechanisms. Here, we discuss a recent in vitro study by Eric Denkers and colleagues that focused on the modulation of gene transcription of host macrophages stimulated by lipopolysaccharide (LPS) following infection with T. gondii. The parasite was able to block the response of macrophages to LPS, a major immunostimulatory component of Gram negative bacteria, thus possibly avoiding the hyperinflammatory response of the host to gut microflora, among which Gram negative bacteria are abundant.
Indexed as
Identifiers
16904378What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.