ReviewCurrent rheumatology reports2006
Clinical manifestations and pathogenesis of hydroxyapatite crystal deposition in juvenile dermatomyositis.
Review in Current rheumatology reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Reliability of durometry to assess firmness of calcinosis lesions in Juvenile and adult dermatomyositis.PloS one · 2026Article
- [Advances in the diagnostics and treatment of juvenile dermatomyositis].Zeitschrift fur Rheumatologie · 2024Review
- Role of mitochondria in the myopathy of juvenile dermatomyositis and implications for skeletal muscle calcinosis.Journal of autoimmunity · 2023Article
- Calcinosis in dermatomyositis: Origins and possible therapeutic avenues.Best practice & research. Clinical rheumatology · 2022Review
- Mitochondrial Calcification.Immunometabolism · 2021Article
- Calcinosis Biomarkers in Adult and Juvenile Dermatomyositis.Autoimmunity reviews · 2020Review
- Calcinosis in juvenile dermatomyositis: frequency, risk factors and outcome.Rheumatology international · 2016Article
- The presentation, assessment, pathogenesis, and treatment of calcinosis in juvenile dermatomyositis.Current rheumatology reports · 2014Review
- Connective tissue mineralization in Abcc6-/- mice, a model for pseudoxanthoma elasticum.Matrix biology : journal of the International Society for Matrix Biology · 2012Article
- Microstructure and mineral composition of dystrophic calcification associated with the idiopathic inflammatory myopathies.Arthritis research & therapy · 2009Article
- Calcium orthophosphates (CaPOProgress in biomaterialsArticle
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathologic deposition of mineral in the form of bone-like hydroxyapatite is a frequent occurrence in juvenile dermatomyositis (JDM) and other connective tissue diseases. Although the sizes of the mineral crystals in JDM are similar to those in bone, there is much more mineral in the deposits than there is in bone. Bone matrix proteins also accumulate associated with the deposits. The reasons for the formation of these deposits are not known. It is our hypothesis that persistent inflammation is a component of JDM and other hydroxyapatite deposition diseases. Other contributing factors are genetic, environmental, and physical chemical. This paper discusses the influence of inflammation on the deposition of hydroxyapatite, with emphasis on the clinical and environmental factors that may facilitate the formation of calcific deposits in JDM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.