ReviewThe EMBO journal2006
Gene expression within a dynamic nuclear landscape.
Review in The EMBO journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Imaging of DNA and RNA in Living Eukaryotic Cells to Reveal Spatiotemporal Dynamics of Gene Expression.Annual review of biochemistry · 2020Review
- Connecting the dots of RNA-directed DNA methylation in Arabidopsis thaliana.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2014Review
- A method for in silico identification of SNAIL/SLUG DNA binding potentials to the E-box sequence using molecular dynamics and evolutionary conserved amino acids.Journal of molecular modeling · 2013Article
- The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing.PLoS biology · 2011Article
- The life of an mRNA in space and time.Journal of cell science · 2010Article
- The architecture of functional neighborhoods within the mammalian cell nucleus.Advances in enzyme regulation · 2010Review
- Evolution of the global internal dynamics of a living cell nucleus during interphase.Biophysical journal · 2009Article
- Single-molecule dynamics of nuclear mRNA.F1000 biology reports · 2009Article
- Organization, integration, and assembly of genetic and epigenetic regulatory machinery in nuclear microenvironments: implications for biological control in cancer.Annals of the New York Academy of Sciences · 2009Article
- How to build a paraspeckle.Genome biology · 2009Review
- Spatio-temporal dynamics of replication and transcription sites in the mammalian cell nucleus.Chromosoma · 2008Article
- Regulation of TATA-binding protein dynamics in living yeast cells.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Genetic and epigenetic regulation in nuclear microenvironments for biological control in cancer.Journal of cellular biochemistry · 2008Review
- Article
- Intranuclear trafficking of episomal DNA is transcription-dependent.Molecular therapy : the journal of the American Society of Gene Therapy · 2007Article
- Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins.Current biology : CB · 2007Article
- The dynamics of the alternatively spliced NOL7 gene products and role in nucleolar architecture.Nucleus (Austin, Tex.)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular imaging in living cells or organisms now allows us to observe macromolecular assemblies with a time resolution sufficient to address cause-and-effect relationships on specific molecules. These emerging technologies have gained much interest from the scientific community since they have been able to reveal novel concepts in cell biology, thereby changing our vision of the cell. One main paradigm is that cells stochastically vary, thus implying that population analysis may be misleading. In fact, cells should be analyzed within time-resolved single-cell experiments rather than being compared to other cells within a population. Technological imaging developments as well as the stochastic events present in gene expression have been reviewed. Here, we discuss how the structural organization of the nucleus is revealed using noninvasive single-cell approaches, which ultimately lead to the resolution required for the analysis of highly controlled molecular processes taking place within live cells. We also describe the efforts being made towards physiological approaches within the context of living organisms.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.