ArticlePlant molecular biology2006
ASK1, a SKP1 homolog, is required for nuclear reorganization, presynaptic homolog juxtaposition and the proper distribution of cohesin during meiosis in Arabidopsis.
Article in Plant molecular biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 49 citations in OpenAlex.
- A conserved structural framework accompanies evolutionary divergence and expression specialization in the grapevine SKP1 family.Frontiers in plant science · 2026Article
- SCFScience advances · 2025Article
- Skp1 proteins are structural components of the synaptonemal complex inScience advances · 2024Article
- Integrated cytological and transcriptomic analysis reveals insights into pollen fertility in newly syntheticFrontiers in plant science · 2022Article
- F-box protein CFK1 interacts with and degrades de novo DNA methyltransferase in Arabidopsis.The New phytologist · 2021Article
- SKP1 promotes YAP-mediated colorectal cancer stemness via suppressing RASSF1.Cancer cell international · 2020Article
- Duplication and divergence: New insights into AXR1 and AXL functions in DNA repair and meiosis.Scientific reports · 2020Article
- SKP1 drives the prophase I to metaphase I transition during male meiosis.Science advances · 2020Article
- Comparative study on cytogenetics and transcriptome between diploid and autotetraploid rice hybrids harboring double neutral genes.PloS one · 2020Article
- Stage-Specific Gene Profiling of Germinal Cells Helps Delineate the Mitosis/Meiosis Transition.Plant physiology · 2018Article
- Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis.The Plant journal : for cell and molecular biology · 2018Article
- The F-Box Protein ZYGO1 Mediates Bouquet Formation to Promote Homologous Pairing, Synapsis, and Recombination in Rice Meiosis.The Plant cell · 2017Article
- In Favor of Establishment: Regulation of Chromatid Cohesion in Plants.Frontiers in plant science · 2017Review
- MEIOTIC F-BOX Is Essential for Male Meiotic DNA Double-Strand Break Repair in Rice.The Plant cell · 2016Article
- Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1.BMC plant biology · 2016Article
- BnaC9.SMG7b Functions as a Positive Regulator of the Number of Seeds per Silique in Brassica napus by Regulating the Formation of Functional Female Gametophytes.Plant physiology · 2015Article
- Comprehensive cell-specific protein analysis in early and late pollen development from diploid microsporocytes to pollen tube growth.Molecular & cellular proteomics : MCP · 2014Article
- Chromosome segregation in plant meiosis.Frontiers in plant science · 2014Review
- The conserved function of skp1 in meiosis.Frontiers in genetics · 2012Article
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Nuclear reorganization and juxtaposition of homologous chromosomes at late leptotene/early zygotene are essential steps before chromosome synapsis at pachytene. We report the results of detailed studies, which demonstrate that nuclear reorganization and homolog juxtapositioning processes are defective in a null mutant, ask1-1. Our results from 4, 6-diamino-2-phenylindole (DAPI)-stained spreads showed that the "synizetic knot", which is typically found in wild type (WT) meiosis during late leptotene and zygotene, was missing in the ask1-1 mutant. Furthermore, ask1-1 meiocytes exhibited only limited homolog juxtaposition at centromere regions at early zygotene. Immunodetection of the cohesin protein SYN1 identified ask1 defects in cohesin distribution from zygotene to anaphase I. Analysis of meiotic chromosomes in ask1-1 and syn1 single mutants, as well as an ask1-1 syn1 double mutant indicate that ASK1 is required for normal SYN1 distribution during meiotic prophase I and suggest that ask1 associated defects may be primarily related to SYN1 mislocalization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.