Evidence map›Paper›PMID 16897394›Full record

ArticleJournal of autism and developmental disorders2006

Social escape behaviors in children with fragile X syndrome.

Scott Hall, Marie DeBernardis, Allan Reiss

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of autism and developmental disorders, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Developmental studies in fragile X syndrome.Journal of neurodevelopmental disorders · 2020
    Review
  13. A novel eye-tracking paradigm for indexing social avoidance-related behavior in fragile X syndrome.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Early gesture use in fragile X syndrome.Journal of intellectual disability research : JIDR · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scott HallBehavioral Neurogenetics Research Center, Rm 1367, Department of Psychiatry and Behavioral Sciences, Stanford University, 401 Quarry Road, Stanford, CA 94305-5795, USA. hallss@stanford.edu
Marie DeBernardis
Allan Reiss

Funding

NEUROPSYCHIATRIC-MOLECULAR ASSOCIATIONS IN FRAGILE X SYNR01MH050047 · NIMH · STANFORD UNIVERSITY · PI REISS, ALLAN L · 1993 to 2022
$12.5M
NEUROPSYCHIATRY OF FRAGILE X AND OTHER GENETIC DISORDERSK02MH001142 · NIMH · STANFORD UNIVERSITY · PI REISS, ALLAN L · 1994 to 2003
$615k
NIMH NIH HHS MH01142NIMH NIH HHS MH50047NIMH NIH HHS R01 MH050047
6 · The paper itself

Abstract

Social escape behavior is a common behavioral feature of individuals with fragile X syndrome (fraX). In this observational study, we examined the effect of antecedent social and performance demands on problem behaviors in four conditions: face-to-face interview, silent reading, oral reading and a singing task. Results showed that problem behaviors were significantly more likely to occur during the interview and singing conditions. Higher levels of salivary cortisol were predictive of higher levels of fidgeting behavior and lower levels of eye contact in male participants. There were no associations between level of FMRP expression and social escape behaviors. These data suggest that specific antecedent biological and environmental factors evoke social escape behaviors in fragile X syndrome.

Indexed as

Escape ReactionFixation, OcularSocial BehaviorAdolescentChildFemaleFragile X SyndromeHumansMaleObserver Variation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.