Evidence map›Paper›PMID 16896848›Full record

ArticleIntensive care medicine2006

Incidence, risk factors and prognosis of changes in serum creatinine early after aortic abdominal surgery.

Christoph Ellenberger, Alexandre Schweizer, John Diaper, Afksendiyos Kalangos, Nicolas Murith, Gregory Katchatourian, Aristote Panos, Marc Licker

Abstract read
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Article in Intensive care medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 87 citations in OpenAlex.

  1. Trial
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  6. Postoperative Intensive Care Management of Aortic Repair.Journal of personalized medicine · 2022
    Review
  7. Review
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  10. The Risk Factors and Outcomes of Acute Kidney Injury after Thoracic Endovascular Aortic Repair.The Korean journal of thoracic and cardiovascular surgery · 2016
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  19. Temporary perioperative decline of renal function is an independent predictor for chronic kidney disease.Clinical journal of the American Society of Nephrology : CJASN · 2010
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Christoph EllenbergerAnesthetics and Critical Care, University Hospital, rue Micheli-Ducrest, 1211, Genève 14, Switzerland.
Alexandre Schweizer
John Diaper
Afksendiyos Kalangos
Nicolas Murith
Gregory Katchatourian
Aristote Panos
Marc Licker
University Hospital of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo determine the incidence, risk factors, and prognostic implications of serum creatinine changes following major vascular surgery.

designObservational study. SETTINGS: University hospital. PATIENTS: Cohort of 599 consecutive patients undergoing elective abdominal aortic surgery.

interventionsReview of prospectively collected data from 1993 to 2004. MEASUREMENTS AND

resultsThe receiver-operator characteristic (ROC) curve analysis was used to detect the best threshold for postoperative elevation in serum creatinine (Delta Creat) in relation to major complications. A cut-off value of +0.5 mg/dl was selected to define renal dysfunction (RD(0.5) group, n=91; no RD(0.5), n=508) that was associated with higher mortality (7.7% in RD(0.5) group vs 1.4% in no RD(0.5) group, P<0.05), rate of admission to the ICU (34% vs 13%, P<0.05), and incidence of cardiovascular (9% vs 4%, P<0.05), respiratory (21% vs 7%, P<0.05), surgical (24% vs 10%, P<0.05), and septic complications (9% vs 3%, P<0.05). After multivariate analysis with logistic regression, renal dysfunction was independently related to low preoperative creatinine clearance [<40 ml/min; odds ratio (OR) 1.5, 95% confidence interval (CI) 1.1-3.9], prolonged renal ischemic time (>40 min; OR, 3.8, 95% CI, 1.9-7.2), blood transfusion (>5 units; OR, 1.9, 95% CI 1.2-6.1), and rhabdomyolysis (OR, 3.6, 95% CI 1.7-7.9).

conclusionsPostoperative RD(0.5) (Delta Creat >0.5 mg/dl) occurs in 15% of vascular patients and carries a bad prognosis. Preoperative renal insufficiency and factors related to the complexity of surgery are the main predictors of renal dysfunction.

Indexed as

Acute Kidney InjuryAgedAortic Aneurysm, AbdominalBiomarkersCreatinineFemaleHumansIncidenceLogistic ModelsMaleMultivariate AnalysisPostoperative ComplicationsPrognosisProspective StudiesRisk FactorsROC CurveBiomarkersCreatinine

Identifiers

PMID16896848
OpenAlexW1974663810

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.